CAJ | 학술논문

与食管癌放疗敏感性相关的肿瘤标记物按存在部位可分为组织学肿瘤标记物和血清学肿瘤标记物,前者包括乏氧诱导因子-1α、环氧合酶-2、p53蛋白、p21蛋白、表皮生长因子受体、增殖细胞核抗原、Survivin蛋白等,后者包括血管内皮生长因子、细胞角蛋白19片段抗原21-1等,对其检测有利于预测食管癌放疗敏感性并制定合理的治疗方案.
여식관암방료민감성상관적종류표기물안존재부위가분위조직학종류표기물화혈청학종류표기물,전자포괄핍양유도인자-1α、배양합매-2、p53단백、p21단백、표피생장인자수체、증식세포핵항원、Survivin단백등,후자포괄혈관내피생장인자、세포각단백19편단항원21-1등,대기검측유리우예측식관암방료민감성병제정합리적치료방안.
Tumor markers associated with the radiosensitivity of esophageal carcinoma are mainly divid-ed into tissue tumor markers and serum tumor markers. Tissue tumor markers include hypoxia inducible factor-1α, cyclooxygenase-2, p53 protein, p21 protein, epidermal growth factor receptor, Ki67 and Survivin, while serum tumor markers include vascular endothelial growth factor, squamous cell carcinoma-antigen and so on. Detection of these markers may be helpful for predicting the radiosensitivity of esophageal carcinoma and making optimal treatment plans.