CAJ | 학술논문

新生儿高氧肺损伤是临床高氧治疗后较常见的并发症,目前尚无特异有效的防治方法.最近研究表明生长因子、骨髓间充质干细胞、促红细胞生成素、抗炎及抗氧化剂在新生儿高氧肺损伤的肺修复及保护中发挥了重要作用.该文综述以上分子系统在延缓和逆转新生儿高氧肺损伤病理过程中的作用机制.
신생인고양폐손상시림상고양치료후교상견적병발증,목전상무특이유효적방치방법.최근연구표명생장인자、골수간충질간세포、촉홍세포생성소、항염급항양화제재신생인고양폐손상적폐수복급보호중발휘료중요작용.해문종술이상분자계통재연완화역전신생인고양폐손상병리과정중적작용궤제.
Hyperoxia-induced lung injury in neonatal is a common complication after the clinical high oxygen therapy. There is not specific and effective prevention and treatment. Recent research suggests that many factor play an important role in the repair and protection of hyperoxia-induced lung injury in neonatal, such as growth factor, bone marrow mesenchymal stem cells,erythropoietin, anti-chemokine and anti-oxidation. The article reviews the molecular systems mechanisms in the pathologic process of hyperroxia-induced lung injury in neonatal.