CAJ | 학술논문

目的利用光学相干断层扫描(OCT)等方法检测LASIK术后泪膜的变化,探讨LASIK对患者泪膜的影响及OCT检测泪膜的可行性.方法对56例(112只眼)近视患者行LASIK手术治疗,利用光学相干断层扫描(OCT)等方法检测,观察术前,术后1周,1个月,3个月泪膜变化.结果利用OCT检查发现术后1周泪河高度、泪河深度、泪河截面积有显著变化(P＜0.05).SchirmerI试验表明术后1周泪液分泌最少；荧光素染色评分表明,术后1周角膜上皮缺损最显著,BUT显示术后1周泪液稳定性最差.结论 OCT具有非侵人性及可重复性,并有定量检查的功能,有可能成为临床上泪膜检测的重要方法.
목적 이용광학상간단층소묘(OCT)등방법검측LASIK술후루막적변화,탐토LASIK대환자루막적영향급OCT검측루막적가행성.방법 대56례(112지안)근시환자행LASIK수술치료,이용광학상간단층소묘(OCT)등방법검측,관찰술전,술후1주,1개월,3개월루막변화.결과 이용OCT검사발현술후1주루하고도、루하심도、루하절면적유현저변화(P＜0.05).SchirmerI시험표명술후1주루액분비최소；형광소염색평분표명,술후1주각막상피결손최현저,BUT현시술후1주루액은정성최차.결론 OCT구유비침인성급가중복성,병유정량검사적공능,유가능성위림상상루막검측적중요방법.
Objective To investigate the alteration of tear film after LASIK with optical coherence tomography (OCT) and the effect of the operation on tear film and whether OCT can measure the tear film. Methods Tear film were measured in both eyes of 56 patients (112 eyes) before LASIK and at 1 week,1 month,3 months after LASIK with several ways including OCT.Results The information given by OCT indicated that tear meniscus height (TMH),tear meniscus depth (TMD) and tear meniscus area (TMA) had significant differences at 1 week after LASIK (P ＜0.05).In SchirmerI test,tear secretion was mostly limited at 1 week after LASIK.Fluorescein showed that corneal epithelial defect was the most significant,and the break-up time indicated that tear film stability was the worst at 1 week postoperatively. Conclusions With excellent non-invasiveness and repeatability for measuring the tear film,OCT has the function of determining quantity and would become a clinical measurement method.