CAJ | 학술논문

目的探讨动静脉双途径联合化疗治疗结直肠癌肝转移的临床疗效.方法 50例结肠癌肝转移按治疗方法分为A、B两组,A组采用肝动脉化疗栓塞加静脉全身化疗,B组采用单纯静脉全身化疗,观察两组副反应、肝内病灶大小变化情况及生存率.结果两组副反应发生率差异无统计学意义(x2 =3.95,P＞ 0.05),A组肝内病灶体积缩小或稳定高于B组(P＜0.05),A组1年、3年生存率分别为84％和64％,明显高于B组的56％和36％(均P＜0.05).结论动静脉双途径联合化疗治疗结肠癌肝转移疗效好,副反应少,能明显提高生存率.
목적 탐토동정맥쌍도경연합화료치료결직장암간전이적림상료효.방법 50례결장암간전이안치료방법분위A、B량조,A조채용간동맥화료전새가정맥전신화료,B조채용단순정맥전신화료,관찰량조부반응、간내병조대소변화정황급생존솔.결과 량조부반응발생솔차이무통계학의의(x2 =3.95,P＞ 0.05),A조간내병조체적축소혹은정고우B조(P＜0.05),A조1년、3년생존솔분별위84％화64％,명현고우B조적56％화36％(균P＜0.05).결론 동정맥쌍도경연합화료치료결장암간전이료효호,부반응소,능명현제고생존솔.
Objective To explore the clinical effect of transcatheter hepatic arterial chemoembolization and systemic chemotherapy on colorectal cancer with hepatic metastasis.Methods 50 cases of colon cancer with hepatic metastasis according to treatment methods were divided into A,B group.A group treated by TACE plus intravenous chemotherapy,B group treated by intravenous chemotherapy alone.Side effects,changes in liver tumor size and survival rate were observed.Results The incidence of side effects of two groups had no significant difference ( P ＞ 0.05 ).A group of liver lesions smaller in size or stable is more than in group B( P ＜0.05 ).A group of 1 year,3 years survival rate is 84％ and 64％ respectively,which is higher than B group 56％ and 36％ ( all P ＜ 0.05 ).Conclusion Transcatheter hepatic arterial chemoembolization and systemic chemotherapy is a safe and effective treatment of colon cancer with hepatic metastasis,it can obviously raise the survival rate.