CAJ | 학술논문

目的探讨超声B -flow血流成像(BFI)检查急性脑梗死患者颈动脉斑块的诊断价值,并与超声造影结果比较,评估其发现斑块内微小血流的能力.方法 2008年9月至201 1年9月,运用BFI对63例颈动脉斑块患者进行斑块内微小血流信号检测,其中急性脑梗死组48例,无症状对照组15例,将检测结果与症状及斑块回声进行相关分析,并根据超声造影增强特点分级后与BFI结果行对照研究.结果共发现184个斑块,急性脑梗死组140个斑块,对照组44个斑块.在急性脑梗死组,BFI在22个斑块内发现微小信号,阳性率为15.7％ (22/140),而对照组仅在1个斑块内发现微小信号,阳性率为2.3％ (1/44),差异有统计学意义(P =0.037).BFI在超声造影分级Ⅰ～Ⅳ级患者中发现微小血流信号的阳性率分别为4.8％(1/21)、2/18、8/17、4/7.BFI发现微小血流信号在Ⅲ级比率明显高于Ⅰ级和Ⅱ级,差异均有统计学意义(P =0.005,P=0.027),但Ⅲ级与Ⅳ级比较差异无统计学意义(P=1.000).结论 BFI能有效发现急性脑梗死患者颈动脉易损斑块内微小血流,且超声造影增强Ⅲ级、Ⅳ级的颈动脉斑块比Ⅰ、Ⅱ级更易被BFI检测出斑块内微小血流.
목적 탐토초성B -flow혈류성상(BFI)검사급성뇌경사환자경동맥반괴적진단개치,병여초성조영결과비교,평고기발현반괴내미소혈류적능력.방법 2008년9월지201 1년9월,운용BFI대63례경동맥반괴환자진행반괴내미소혈류신호검측,기중급성뇌경사조48례,무증상대조조15례,장검측결과여증상급반괴회성진행상관분석,병근거초성조영증강특점분급후여BFI결과행대조연구.결과 공발현184개반괴,급성뇌경사조140개반괴,대조조44개반괴.재급성뇌경사조,BFI재22개반괴내발현미소신호,양성솔위15.7％ (22/140),이대조조부재1개반괴내발현미소신호,양성솔위2.3％ (1/44),차이유통계학의의(P =0.037).BFI재초성조영분급Ⅰ～Ⅳ급환자중발현미소혈류신호적양성솔분별위4.8％(1/21)、2/18、8/17、4/7.BFI발현미소혈류신호재Ⅲ급비솔명현고우Ⅰ급화Ⅱ급,차이균유통계학의의(P =0.005,P=0.027),단Ⅲ급여Ⅳ급비교차이무통계학의의(P=1.000).결론 BFI능유효발현급성뇌경사환자경동맥역손반괴내미소혈류,차초성조영증강Ⅲ급、Ⅳ급적경동맥반괴비Ⅰ、Ⅱ급경역피BFI검측출반괴내미소혈류.
Objective To detect the micro flow signals of carotid plaque by ultrasound B-flow imaging (BFI) and elucidate its relationship with acute cerebral infarction.Methods A total of 63 patients with carotid plaques were divided into 2 groups.acute cerebral infarction (ACI,n =48) and control (n =15).BFI was used to detect the micro flow signals of plaques and comparisons were made with the categorizing results of contrast enhanced ultrasound (CEU).The data were analyzed between two methods.Results The micro flow signals were detected in 15.7％ (22/140)patients in the ACI group vs.2.3％(1/44) in the control group.There were more signals in hypoechoic plaques.The detection percentage of micro flow in grade Ⅲ was significantly higher than that in grades Ⅰ and Ⅱ with CEU (P =0.005,P =0.027).No significant differences existed between grades Ⅲ and Ⅳ (P =1.000).Conclusion BFI can detect effectively the micro flow signals of carotid plaques and this characteristic is correlated with the symptoms of ACI.