CAJ | 학술논문

目的总结分析以血小板减少为主要临床表现的HIV/AIDS患者的临床特点,治疗方法,随访情况及转归.方法回顾性分析新疆医科大学第一附属医院感染性疾病中心2004年1月至2011年11月收治的16例艾滋病患者的一般情况,临床表现,体征及抗病毒方案、CD4细胞计数,血小板计数、观察临床转归及预后情况.结果该组患者均以血小板减少为主要临床表现,比较高效抗逆转录病毒治疗前,治疗后第1、3、6、12个月的血小板计数及CD4,均有明显改善,其中14例患者血小板升至(113 ～465)×109/L.并无机会性感染及HIV相关的死亡事件出现.结论在HIV/AIDS患者中,以血小板减少为主要表现的病例及时开展高效抗逆转录病毒治疗,可有效改善预后及转归.
목적 총결분석이혈소판감소위주요림상표현적HIV/AIDS환자적림상특점,치료방법,수방정황급전귀.방법 회고성분석신강의과대학제일부속의원감염성질병중심2004년1월지2011년11월수치적16례애자병환자적일반정황,림상표현,체정급항병독방안、CD4세포계수,혈소판계수、관찰림상전귀급예후정황.결과 해조환자균이혈소판감소위주요림상표현,비교고효항역전록병독치료전,치료후제1、3、6、12개월적혈소판계수급CD4,균유명현개선,기중14례환자혈소판승지(113 ～465)×109/L.병무궤회성감염급HIV상관적사망사건출현.결론 재HIV/AIDS환자중,이혈소판감소위주요표현적병례급시개전고효항역전록병독치료,가유효개선예후급전귀.
Objective To summarize the major clinical features,treatment,follow-up and outcomes of acquired immune deficiency syndrome (AIDS) patients with prominent thrombocytopenia.Methods The manifestations,signs,anti-virus regimens,CD4 cell count,platelet count,prognosis and outcomes of 10 AIDS patients with prominent thrombocytopenia were collected and analyzed. Results After the administration of highly active antiretroviral therapy,platelet count and CD4 significantly improved during a follow-up period up to 12 months No opportunistic infections and HIV-related deaths occurred.Conclusion The HIV/AIDS patients with prominent thrombocytopenia should start highly active antiretroviral therapy so as to effectively improve the prognosis and outcome.