CAJ | 학술논문

肾素直接抑制剂阿利克伦是一种新型、安全、有效的口服抗高血压药物,并且具有肾脏保护、减少左心窒肥厚等作用,可以单用或者与ACE抑制剂(如雷米普利)、Aug Ⅱ受体阻滞剂(如缬沙坦)和噻嗪类利尿剂等降压药物联合使用,降压作用具有剂量依赖性,病人耐受性良好.
신소직접억제제아리극륜시일충신형、안전、유효적구복항고혈압약물,병차구유신장보호、감소좌심질비후등작용,가이단용혹자여ACE억제제(여뢰미보리)、Aug Ⅱ수체조체제(여힐사탄)화새진류이뇨제등강압약물연합사용,강압작용구유제량의뢰성,병인내수성량호.
The oral direct renin inhibitor aliskiren is a novel , safe and ef-fective antihypertensive agent, it has renoprotection and reduces left ven-tricular mass. Aliskiren can be used as monotherapy or in combination with angiotensin converting enzyme inhibitors (ramipril), angiotensin re-ceptor blockers (valsartan) and hydrochlorothiazide diuretics in patients with hypertension. It has dose-dependent antihypertensive effect and good tolerability of patients.