中华神经科杂志
中華神經科雜誌
중화신경과잡지
Chinese Journal of Neurology
2012年
4期
254-258
,共5页
赵振宇%韩红星%孙贞超%蒋建章%张晨
趙振宇%韓紅星%孫貞超%蔣建章%張晨
조진우%한홍성%손정초%장건장%장신
先兆子痫%子痫%后部白质脑病综合征%脑水肿%磁共振成像
先兆子癇%子癇%後部白質腦病綜閤徵%腦水腫%磁共振成像
선조자간%자간%후부백질뇌병종합정%뇌수종%자공진성상
Pre-eclampsia%Eclampsia%Posterior leukoencephalopathy syndrome%Brain edema%Magnetic resonance imaging
目的 探讨子痫前期或子痫致可逆性后部脑病综合征( posterior reversible encephalopathy syndrome,PRES)的临床及影像学特点.方法 选择子痫前期或子痫致PRES患者21例,采用回顾性分析方法对临床症状及脑磁共振成像(magnetic resonance imaging,MRI)资料进行分析.结果 主要临床症状:21例患者中癫痫发作18例,头痛16例,意识状态改变15例,视觉障碍12例;PRES病灶分布:顶、枕叶20例,额叶14例,颞叶11例,基底节区11例,胼胝体压部4例,小脑半球3例,脑干1例;PRES病灶分布模式:经典型7例,全脑型7例,额上沟型6例,部分或不对称型1例.结论 子痫前期或子痫致PRES临床症状典型,除顶、枕叶外,额叶、颞叶、基底节区等部位累及常见,多见3种主要病灶分布模式,准确识别其影像学表现对正确诊断具有重要意义.
目的 探討子癇前期或子癇緻可逆性後部腦病綜閤徵( posterior reversible encephalopathy syndrome,PRES)的臨床及影像學特點.方法 選擇子癇前期或子癇緻PRES患者21例,採用迴顧性分析方法對臨床癥狀及腦磁共振成像(magnetic resonance imaging,MRI)資料進行分析.結果 主要臨床癥狀:21例患者中癲癇髮作18例,頭痛16例,意識狀態改變15例,視覺障礙12例;PRES病竈分佈:頂、枕葉20例,額葉14例,顳葉11例,基底節區11例,胼胝體壓部4例,小腦半毬3例,腦榦1例;PRES病竈分佈模式:經典型7例,全腦型7例,額上溝型6例,部分或不對稱型1例.結論 子癇前期或子癇緻PRES臨床癥狀典型,除頂、枕葉外,額葉、顳葉、基底節區等部位纍及常見,多見3種主要病竈分佈模式,準確識彆其影像學錶現對正確診斷具有重要意義.
목적 탐토자간전기혹자간치가역성후부뇌병종합정( posterior reversible encephalopathy syndrome,PRES)적림상급영상학특점.방법 선택자간전기혹자간치PRES환자21례,채용회고성분석방법대림상증상급뇌자공진성상(magnetic resonance imaging,MRI)자료진행분석.결과 주요림상증상:21례환자중전간발작18례,두통16례,의식상태개변15례,시각장애12례;PRES병조분포:정、침협20례,액협14례,섭협11례,기저절구11례,변지체압부4례,소뇌반구3례,뇌간1례;PRES병조분포모식:경전형7례,전뇌형7례,액상구형6례,부분혹불대칭형1례.결론 자간전기혹자간치PRES림상증상전형,제정、침협외,액협、섭협、기저절구등부위루급상견,다견3충주요병조분포모식,준학식별기영상학표현대정학진단구유중요의의.
Objective To investigate the clinical and radiologic features of posterior reversible encephalopathy syndrome (PRES) associated with preeclampsia-eclampsia.Methods Twenty-one cases of PRES associated with preeclampsia-eclampsia were retrospectively studied on some aspects of clinical and radiologic features.Results The most common clinical presentations were seizures( 18 cases ),headache (16 cases),altered mentation (15 cases) and vision change (12 cases). Vasogenic edema lesions distributed in the parietal or occipital lobe (20 cases),the frontal lobes (14 cases),temporal lobes ( 11 cases), and basal ganglia (11 cases). The splenium involvement occurred in 4 cases,cerebellar hemispheres and brain stem involvement was prcscnted in 3 cases and 1 case separately. Three major patterns of PRES included dominant parietal-occipital (7 cases),the holohemispheric watershed (7 cases),and superior frontal sulcal (6 cases).Partial and asymmetric expression of PRES only occurred in 1 case.Conclusions The clinical features of PRES associated with preeclampsia-eclampsia are typical.Except the parietal or occipital lobe,involvement of the frontal lobe,temporal lobe and basal ganglia is common,followed by the occasional presence of the splenium,cerebellar hemispheres and brain stem.Three primary PRES patterns are noted,occasional with partial and asymmetric expression of PRES. Awareness of these typical and variable characteristics is important to recognize the PRES ncurotoxicity morc accurately when PRES present.