国际放射医学核医学杂志
國際放射醫學覈醫學雜誌
국제방사의학핵의학잡지
INTERNATIONAL JOURNAL OF RADIATION MEDICINE AND NUCLEAR MEDICINE
2010年
6期
357-359
,共3页
肾小球滤过率%99m锝五乙酸盐%胱抑素C
腎小毬濾過率%99m锝五乙痠鹽%胱抑素C
신소구려과솔%99m득오을산염%광억소C
Glomerular filtration rate%Technetium Tc 99m pentetate%Cystatin C
目的 比较99Tcm-二亚乙基三胺五乙酸(99Tcm-DTPA)肾动态显像和血清胱抑素C测定两种方法在评价肾小球滤过功能中的差别.方法 随机抽取100例患者,其中高血压病患者38例、肾脏病患者35例、动脉硬化性闭塞症患者10例、糖尿病患者9例、其他疾病患者8例.分别通过99Tcm-DTPA肾动态显像法和血清胱抑素C测定法评估肾小球滤过功能.结果 两种方法所测得的肾小球滤过率(GFR)差异无统计学意义(t=1.591,P＞0.05),且呈线性相关(r=0.809,P＜0.01);放射性核素肾动态显像法在测定GFR的同时,还可以获得分肾功能,观察双肾血流灌注和排泄状况.结论 用99Tcm-DTPA肾动态显像与血清胱抑素C测定两种方法评估GFR,结果无显著差异,且相关性很好.前者可以获得分肾功能,对肾功能状态的评估更为全面;而后者测定方法简便、省时,且价廉,更适合于对临床患者肾功能的筛查.
目的 比較99Tcm-二亞乙基三胺五乙痠(99Tcm-DTPA)腎動態顯像和血清胱抑素C測定兩種方法在評價腎小毬濾過功能中的差彆.方法 隨機抽取100例患者,其中高血壓病患者38例、腎髒病患者35例、動脈硬化性閉塞癥患者10例、糖尿病患者9例、其他疾病患者8例.分彆通過99Tcm-DTPA腎動態顯像法和血清胱抑素C測定法評估腎小毬濾過功能.結果 兩種方法所測得的腎小毬濾過率(GFR)差異無統計學意義(t=1.591,P＞0.05),且呈線性相關(r=0.809,P＜0.01);放射性覈素腎動態顯像法在測定GFR的同時,還可以穫得分腎功能,觀察雙腎血流灌註和排洩狀況.結論 用99Tcm-DTPA腎動態顯像與血清胱抑素C測定兩種方法評估GFR,結果無顯著差異,且相關性很好.前者可以穫得分腎功能,對腎功能狀態的評估更為全麵;而後者測定方法簡便、省時,且價廉,更適閤于對臨床患者腎功能的篩查.
목적 비교99Tcm-이아을기삼알오을산(99Tcm-DTPA)신동태현상화혈청광억소C측정량충방법재평개신소구려과공능중적차별.방법 수궤추취100례환자,기중고혈압병환자38례、신장병환자35례、동맥경화성폐새증환자10례、당뇨병환자9례、기타질병환자8례.분별통과99Tcm-DTPA신동태현상법화혈청광억소C측정법평고신소구려과공능.결과 량충방법소측득적신소구려과솔(GFR)차이무통계학의의(t=1.591,P＞0.05),차정선성상관(r=0.809,P＜0.01);방사성핵소신동태현상법재측정GFR적동시,환가이획득분신공능,관찰쌍신혈류관주화배설상황.결론 용99Tcm-DTPA신동태현상여혈청광억소C측정량충방법평고GFR,결과무현저차이,차상관성흔호.전자가이획득분신공능,대신공능상태적평고경위전면;이후자측정방법간편、성시,차개렴,경괄합우대림상환자신공능적사사.
Objective To compare the difference between 99Tcm-diethylenetriaminepentaacetic acid (99Tcm-DTPA) renal dynamic imaging and measurement of serum cystatin C in evaluation of glomerular filtration rate (GFR). Methods One hundred patients were selected at random, 38 cases with hy-pertension, 35with nephrosis, 10 with arteriosclerosis obliterans, 9 with diabetes and 8 with other diseases. Evaluation of patients'GFR was made separately by 99Tcm-DTPA renal dynamic imaging and measurement of serum cystatin C. Results No significant difference of GFR was found between the two methods (t=1.591, P＞0.05 ),and linear correlation was showed as well (r=0.809, P＜0.01 ). The imaging also revealed the function of individaul kidney, renal blood perfusion and excretory function besides GFR. Conclusions Results of GFR from the two methods revealed no significant difference and they were highly correlated. 99Tcm-DTPA renal dynamic imaging could reveal the individual renal function and provide a more comprehensive evaluation of renal function while the measurement of serum cystatin C was simple and convenient, timesaving, economic, and more suit-able for screening patients'renal function clinically.
