中国医师进修杂志
中國醫師進脩雜誌
중국의사진수잡지
CHINESE JOURNAL OF POSTGRADUATES OF MEDICINE
2011年
31期
9-12
,共4页
糖尿病,2型%糖化血红蛋白
糖尿病,2型%糖化血紅蛋白
당뇨병,2형%당화혈홍단백
Diabetes mellitus%type 2%Hemoglobin A1c
目的 研究血糖、治疗方案、病程、年龄、糖尿病教育、文化程度、自我血糖监测对糖化血红蛋白的影响.方法 78例2型糖尿病患者分别按血糖、治疗方案、年龄、病程、糖尿病教育、文化程度、自我血糖监测这几项因素的不同程度分为两组,比较两组间糖化血红蛋白的变化.结果 空腹血糖≤6.1 mmol/L组(30例)较空腹血糖>6.1 mmol/L组(48例),餐后2h血糖≤8.0 mmol/L组(32例)较餐后2h血糖>8.0 mmol/L组(46例),胰岛素治疗组(27例)较非胰岛素治疗组(51例),联合口服降糖药治疗组(36例)较单一口服降糖药治疗组(15例),年龄≤65岁组(41例)较年龄>65岁组(37例),病程≤10年组(39例)较病程> 10年组(39例),文化程度高中及以上组(34例)较文化程度高中以下组(44例),糖尿病教育频次≥2次/月组(20例)较糖尿病教育频次<2次/月组(58例),自我血糖监测频次≥2次/周组(19例)较自我血糖监测频次<2次/周组(59例),糖化血红蛋白均下降,分别为(6.7±1.5)%比(7.9±1.3)%、(6.8±1.1)%比(7.8±1.2)%、(6.7±1.5)%比(8.1±1.4)%、(6.8±1.0)%比(8.0±1.6)%、(6.9±1.7)%比(7.4±1.6)%、(6.5±1.2)%比(8.2±1.3)%、(6.9±1.0)%比(7.6±1.4)%、(6.1±1.7)%比(8.0±1.1)%、(6.7±1.1)%比(7.6±1.2)%,差异有统计学意义(P< 0.01或<0.05).结论 血糖、治疗方案、年龄、病程、糖尿病教育、文化程度、自我血糖监测是影响糖化血红蛋白的重要因素.
目的 研究血糖、治療方案、病程、年齡、糖尿病教育、文化程度、自我血糖鑑測對糖化血紅蛋白的影響.方法 78例2型糖尿病患者分彆按血糖、治療方案、年齡、病程、糖尿病教育、文化程度、自我血糖鑑測這幾項因素的不同程度分為兩組,比較兩組間糖化血紅蛋白的變化.結果 空腹血糖≤6.1 mmol/L組(30例)較空腹血糖>6.1 mmol/L組(48例),餐後2h血糖≤8.0 mmol/L組(32例)較餐後2h血糖>8.0 mmol/L組(46例),胰島素治療組(27例)較非胰島素治療組(51例),聯閤口服降糖藥治療組(36例)較單一口服降糖藥治療組(15例),年齡≤65歲組(41例)較年齡>65歲組(37例),病程≤10年組(39例)較病程> 10年組(39例),文化程度高中及以上組(34例)較文化程度高中以下組(44例),糖尿病教育頻次≥2次/月組(20例)較糖尿病教育頻次<2次/月組(58例),自我血糖鑑測頻次≥2次/週組(19例)較自我血糖鑑測頻次<2次/週組(59例),糖化血紅蛋白均下降,分彆為(6.7±1.5)%比(7.9±1.3)%、(6.8±1.1)%比(7.8±1.2)%、(6.7±1.5)%比(8.1±1.4)%、(6.8±1.0)%比(8.0±1.6)%、(6.9±1.7)%比(7.4±1.6)%、(6.5±1.2)%比(8.2±1.3)%、(6.9±1.0)%比(7.6±1.4)%、(6.1±1.7)%比(8.0±1.1)%、(6.7±1.1)%比(7.6±1.2)%,差異有統計學意義(P< 0.01或<0.05).結論 血糖、治療方案、年齡、病程、糖尿病教育、文化程度、自我血糖鑑測是影響糖化血紅蛋白的重要因素.
목적 연구혈당、치료방안、병정、년령、당뇨병교육、문화정도、자아혈당감측대당화혈홍단백적영향.방법 78례2형당뇨병환자분별안혈당、치료방안、년령、병정、당뇨병교육、문화정도、자아혈당감측저궤항인소적불동정도분위량조,비교량조간당화혈홍단백적변화.결과 공복혈당≤6.1 mmol/L조(30례)교공복혈당>6.1 mmol/L조(48례),찬후2h혈당≤8.0 mmol/L조(32례)교찬후2h혈당>8.0 mmol/L조(46례),이도소치료조(27례)교비이도소치료조(51례),연합구복강당약치료조(36례)교단일구복강당약치료조(15례),년령≤65세조(41례)교년령>65세조(37례),병정≤10년조(39례)교병정> 10년조(39례),문화정도고중급이상조(34례)교문화정도고중이하조(44례),당뇨병교육빈차≥2차/월조(20례)교당뇨병교육빈차<2차/월조(58례),자아혈당감측빈차≥2차/주조(19례)교자아혈당감측빈차<2차/주조(59례),당화혈홍단백균하강,분별위(6.7±1.5)%비(7.9±1.3)%、(6.8±1.1)%비(7.8±1.2)%、(6.7±1.5)%비(8.1±1.4)%、(6.8±1.0)%비(8.0±1.6)%、(6.9±1.7)%비(7.4±1.6)%、(6.5±1.2)%비(8.2±1.3)%、(6.9±1.0)%비(7.6±1.4)%、(6.1±1.7)%비(8.0±1.1)%、(6.7±1.1)%비(7.6±1.2)%,차이유통계학의의(P< 0.01혹<0.05).결론 혈당、치료방안、년령、병정、당뇨병교육、문화정도、자아혈당감측시영향당화혈홍단백적중요인소.
Objective To analyze the influencing factors of hemoglobin A1c in type 2 diabetic patients,including blood glucose,anti-diabetic therapeutic regiments,disease course,age,diabetic education,degree-educated,self-monitoring blood glucose.Methods Seventy-eight type 2 diabetic patients were divided into two groups by different degree of blood glucose,anti-diabetic therapeutic regiments,disease course,age,diabetic education,degree-educated,self-monitoring blood glucose.The levels of hemoglobin A1c in two groups were compared.Results There were significant changes in the levels of hemoglobin A1c between fasting blood glucose (FBG) ≤ 6.1 mmol/L group (30 cases) and FBG > 6.1 mmol/L group (48cases),2 h postprandial blood glucose (2hBG) ≤8.0 mmol/L group (32 cases) and 2hBG > 8.0 mmol/L group (46 cases ),insulin treatment group (27 cases) and no-insulin treatment group ( 51 cases ),combined drugs treatment group ( 36 cases ) and single drug treatment group ( 15 cases),age ≤ 65 years old group (41cases) and age >65 years old group (37 cases),disease course≤ 10 years group (39 cases) and disease course > 10 years group( 39 cases),degree-educated above high grade group( 34 cases) and degree-educated below high grade group (44 cases),diabetic education ≥2 times/month group (20 cases) and diabetic education < 2 times/month group (58 cases),self-monitoring blood glucose≥2 times/week group ( 19 cases)and self-monitoring blood glucose < 2 times/week group (59 cases)[ (6.7 ± 1.5 )% vs.(7.9 ± 1.3 )%,(6.8 ±1.1)% vs.(7.8 ± 1.2)%,(6.7 ± 1.5)% vs.(8.1 ± 1.4)%,(6.8 ± l.0)%vs.(8.0 ± 1.6)%,(6.9 ± 1.7)% vs.(7.4 ± 1.6)%,(6.5 ± 1.2)% vs.(8.2 ± 1.3)%,(6.9 ± 1.0)% vs.(7.6 ± 1.4)%,(6.1 ± 1.7)% vs.(8.0 ±1.1 ) %,(6.7 ± 1.1 )% vs.(7.6 ± 1.2)% ] (P < 0.01 or < 0.05 ).Conclusion Blood glucose,anti-diabetic therapeutic regiments,disease course,diabetic,degree-educated,self-monitoring blood glucose are the important factors influencing hemoglobin A1c.