广州化工
廣州化工
엄주화공
GUANGZHOU CHEMICAL INDUSTRY AND TECHNOLOGY
2011年
22期
37-38
,共2页
邻苯二甲酸酐%氨解%脱水%2-氰基苯甲酸
鄰苯二甲痠酐%氨解%脫水%2-氰基苯甲痠
린분이갑산항%안해%탈수%2-청기분갑산
phthalic anhydride%ammonolysis%dehydration%2-cyanobenzoic acid
以邻苯二甲酸酐为原料,通过氨解、脱水、酸化,总收率75%得到2-氰基苯甲酸。此方法原料易得,反应条件温和,操作过程简单,未使用毒性大的氰化盐,产品产率较高,有利于工业化生产。
以鄰苯二甲痠酐為原料,通過氨解、脫水、痠化,總收率75%得到2-氰基苯甲痠。此方法原料易得,反應條件溫和,操作過程簡單,未使用毒性大的氰化鹽,產品產率較高,有利于工業化生產。
이린분이갑산항위원료,통과안해、탈수、산화,총수솔75%득도2-청기분갑산。차방법원료역득,반응조건온화,조작과정간단,미사용독성대적청화염,산품산솔교고,유리우공업화생산。
A novel synthetic method of 2-cyanobenzoic acid was introduced.Ideal product can be got through ammonolysis,dehydration and acidification when the phthalic anhydride was used as raw material.The total yield was achieved to 75%.Comparing to other ordinary methods,this synthetic route had many advantages,such as cheap raw materials,mild reaction conditions,simple operation,and higher yield,especially,high toxic cyanide salt was not used.So it had broad application prospects in industry production.
