CAJ | 학술논문

目的　评价福辛普利对急性心肌梗死(AMI)患者左心功能和左心室重塑的影响。方法　对30例初次前壁AMI患者,发病12 h内开始应用福辛普利治疗,分别于AMI急性期和恢复期进行Killip心功能评价和二维超声心动图(2DE)检查。结果　恢复期福辛普利组心功能及LVEF明显改善(P<0.05)，ASL也相应缩小(P<0.05)。结论　不伴有明显血流动力学障碍的AMI患者,早期应用福辛普利可减轻左心室扩张，改善患者左心功能。
목적　평개복신보리대급성심기경사(AMI)환자좌심공능화좌심실중소적영향。방법　대30례초차전벽AMI환자,발병12 h내개시응용복신보리치료,분별우AMI급성기화회복기진행Killip심공능평개화이유초성심동도(2DE)검사。결과　회복기복신보리조심공능급LVEF명현개선(P<0.05)，ASL야상응축소(P<0.05)。결론　불반유명현혈류동역학장애적AMI환자,조기응용복신보리가감경좌심실확장，개선환자좌심공능。
Objective　To evaluate the influence of fosinopril on the left ventricular function and remodeling after AMI.Methods　Thirty patients with acute myocardial infarction of anterior wall treated with fosinopril in 12 hours from the attack. The morphology of left ventricle and cardiac function (Killip methods) were assessed by 2DE at acute period and recovery period.Results　Cardiac function and 2DE targets improved during 12 weeks follow-up in fosinopril group(P<0.05).Conclusion　Fosinopril for the patients of AMI without hemodynamics changes may significantly inhibit the ventricular dilatation and improve the cardiac function.