CAJ | 학술논문

目的：检测催乳素在妊高征中的水平及与妊高征的关系。方法：选择正常妊娠妇女89例及妊高征患者52例，分区方法，按妊娠每2周分为8组，按正常妊娠每组的催乳素均值划分3区，即A区（高值区）（x>+s）；B区（中值区）（x+s）～；C区（低值区）～(x+s);利用放射免疫分析法测定正常妊娠中晚期及妊高征催乳素水平。结果：正常妊娠第24周催乳素均值为270mg．L-1，随孕周增加而升高，第34～37周达高峰，峰值为440mg.L-1，后逐渐下降。妊高征组血清催乳素显著高于正常妊娠组；其中31例（59.6%）催乳素在A区，10例（19.3%）在B区，11例(21.1%)在C区。结论：高催乳素水平可能与妊高征发病有关。
목적：검측최유소재임고정중적수평급여임고정적관계。방법：선택정상임신부녀89례급임고정환자52례，분구방법，안임신매2주분위8조，안정상임신매조적최유소균치화분3구，즉A구（고치구）（x>+s）；B구（중치구）（x+s）～；C구（저치구）～(x+s);이용방사면역분석법측정정상임신중만기급임고정최유소수평。결과：정상임신제24주최유소균치위270mg．L-1，수잉주증가이승고，제34～37주체고봉，봉치위440mg.L-1，후축점하강。임고정조혈청최유소현저고우정상임신조；기중31례（59.6%）최유소재A구，10례（19.3%）재B구，11례(21.1%)재C구。결론：고최유소수평가능여임고정발병유관。
Objective: This study was to investigate the relationship betweenserum prolactin and pregnancy-induced hypertension. Method: Maternal serum prolactin was estimated by radioimmunoassay in 89 normal pregnant women and 52 patients with severe pregnancy-induced hypertension at 28 to 42 week gestation. Results: In normal pregnancy, prolactin level increased progressively from a mean value of 270 mg．L-1 in the 24th week to 440 mg.L-1 in the 34th week and decreased progressively from the 38th week to the 40th week. In severe pregnancy-induced hypertension increased progressively too;31 of 52 patients with severe prolactin showed high prolactin levels in zone A(>mean value + standard of prolactin values in the normal pregnancy),10 patients in zone B(mean+standard to mean )and 11 patients in zone C(<mean).Conclusion:These results suggest that high prolactin levels may play an important role in the pathogenesis of severe pregnancy-induced hypertension.