国际检验医学杂志
國際檢驗醫學雜誌
국제검험의학잡지
INTERNATIONAL JOURNAL OF LABORATORY MEDICINE
2009年
7期
653-654
,共2页
烧伤%假单胞菌%铜绿%β内酰胺酶类
燒傷%假單胞菌%銅綠%β內酰胺酶類
소상%가단포균%동록%β내선알매류
Burns%Pseudomonas aeruginosa%beta Lactamases
目的 比较烧伤病区和其他病区铜绿假单胞菌产金属β-内酰胺酶的情况并分析其耐药性,为临床合理选用抗生素提供依据.方法 采用细菌鉴定药敏分析仪进行铜绿假单胞菌的鉴定及药敏试验.同时采用纸片协同法筛选产金属酶的菌株.结果 在检测的68株铜绿假单胞菌中,产金属酶的有9株,占13.2%.烧伤病区产金属酶的有7株(7/32),占21.9%;其他病区产金属酶的有2株(2/36),占5.6%.产酶株对头孢他啶、头孢噻肟、亚胺培南、环丙沙星、阿米卡星、庆大霉素、哌拉西林、氨曲南的耐药率分别为100%、100%、88.9%、66.7%、88.9%、100%、100%、88.9%,远远高于不产金属酶的铜绿假单胞菌.结论 烧伤病区的铜绿假单胞菌的产酶率比其他病区的高,产金属酶的铜绿假单胞菌对临床常用的多种抗生素具有较高的耐药率,临床必须依据药敏实验结果 使用抗生素.
目的 比較燒傷病區和其他病區銅綠假單胞菌產金屬β-內酰胺酶的情況併分析其耐藥性,為臨床閤理選用抗生素提供依據.方法 採用細菌鑒定藥敏分析儀進行銅綠假單胞菌的鑒定及藥敏試驗.同時採用紙片協同法篩選產金屬酶的菌株.結果 在檢測的68株銅綠假單胞菌中,產金屬酶的有9株,佔13.2%.燒傷病區產金屬酶的有7株(7/32),佔21.9%;其他病區產金屬酶的有2株(2/36),佔5.6%.產酶株對頭孢他啶、頭孢噻肟、亞胺培南、環丙沙星、阿米卡星、慶大黴素、哌拉西林、氨麯南的耐藥率分彆為100%、100%、88.9%、66.7%、88.9%、100%、100%、88.9%,遠遠高于不產金屬酶的銅綠假單胞菌.結論 燒傷病區的銅綠假單胞菌的產酶率比其他病區的高,產金屬酶的銅綠假單胞菌對臨床常用的多種抗生素具有較高的耐藥率,臨床必鬚依據藥敏實驗結果 使用抗生素.
목적 비교소상병구화기타병구동록가단포균산금속β-내선알매적정황병분석기내약성,위림상합리선용항생소제공의거.방법 채용세균감정약민분석의진행동록가단포균적감정급약민시험.동시채용지편협동법사선산금속매적균주.결과 재검측적68주동록가단포균중,산금속매적유9주,점13.2%.소상병구산금속매적유7주(7/32),점21.9%;기타병구산금속매적유2주(2/36),점5.6%.산매주대두포타정、두포새우、아알배남、배병사성、아미잡성、경대매소、고랍서림、안곡남적내약솔분별위100%、100%、88.9%、66.7%、88.9%、100%、100%、88.9%,원원고우불산금속매적동록가단포균.결론 소상병구적동록가단포균적산매솔비기타병구적고,산금속매적동록가단포균대림상상용적다충항생소구유교고적내약솔,림상필수의거약민실험결과 사용항생소.
Objective To compare the resistance of metallo-β-lactamase -producting Pseudomonas aeruginosa between burn ward and other wards, so as to provide basis for reasonable use of antimicrobial agents. Methods BD Phoenix-100 bacteria identification and drug sensitivity analyzer was used to detect Pseudomonas aeruginosa and its susceptibility, and disc synergy method was used for the screening of metallo-v-lactamase -producting Pseudomonas aeruginosa. Results Of 68 strains of Pseudomonas aeruginosa, 9 strains (13.2%) were metallo-β-lactamase (MBL) positive. Among the 9metallo-β-lactamase positive strains, 7 strains were from the burn ward and 2 strains from other wards. The resistance rate of the MBL-producing strains to ceftazidime, cefotaxime, imipenem, ciprofloxacin, amikacin, gentamicin, piperacillin and aztreonam was respectively 100.0%, 100. 0%, 88.9%, 66.7%, 88.9%, 100,0%, 100.0%, and 88.9%, obviously higher than that of non-MBL-pro-ducing Pseudomonas aeruginosa. Conclusion The rate of MBL-producing Pseudomonas aeruginosa is obviously higher in burn ward than that in other wards. The resistance of MBL-producing Pseudomonas aeruginosa is high against commonly used antimicrobial agents. Clinical use of antibiotics should he based on the antimicrobial susceptibility test results.
