CAJ | 학술논문

目的探讨2型糖尿病伴室性期前收缩患者窦性心律震荡的变化及与24h尿蛋白的关系. 方法 57例伴室性期前收缩的2型糖尿病患者被分为正常白蛋白尿组(n=18)、微量白蛋白尿组(n=19)、临床白蛋白尿(n=20),记录24h动态心电图,计算及比较各组震荡初始(T0)和震荡斜率(TS). 结果临床白蛋白尿组和微量白蛋白尿组TO[分别为(0.08±0.67)%、(0.07±0.72)%]高于正常白蛋白尿组(-1.79±0.41)%,而TS[分别为(5.09±1.28)ms/R-R、(5.01±1.04)ms/R-R)低于正常自蛋白尿组(8.39±1.05)ms/R-R,差异均有非常显著性意义(P<0.01). 结论 2型糖尿病患者TO明显升高,TS明显下降,其变化程度与24h尿蛋白量密切相关.
목적 탐토2형당뇨병반실성기전수축환자두성심률진탕적변화급여24h뇨단백적관계. 방법 57례반실성기전수축적2형당뇨병환자피분위정상백단백뇨조(n=18)、미량백단백뇨조(n=19)、림상백단백뇨(n=20),기록24h동태심전도,계산급비교각조진탕초시(T0)화진탕사솔(TS). 결과 림상백단백뇨조화미량백단백뇨조TO[분별위(0.08±0.67)%、(0.07±0.72)%]고우정상백단백뇨조(-1.79±0.41)%,이TS[분별위(5.09±1.28)ms/R-R、(5.01±1.04)ms/R-R)저우정상자단백뇨조(8.39±1.05)ms/R-R,차이균유비상현저성의의(P<0.01). 결론 2형당뇨병환자TO명현승고,TS명현하강,기변화정도여24h뇨단백량밀절상관.
Objective To investigate the relationship between heart rate turbulence and 24-hour urine protein in type 2 diabetes mellitus(DM). Methods 57 type 2 DM patients with ventricular premature beat were divided into normoatbu-minuria group (group A, n=18), microalbuminuda group (group B, n=19), albuminuria group (group C, n=20). Turbu-lence onset (TO) and turbulence slope (TS) were calculated based on 24-hour ambulatory ECG and compared among different groups. Results TO was significantly higher in group C (0.08 ± 0.67)% and group B (0.07 ±0.72)%than in group A(-1.79 ± 0.41 }%(all P < 0.01). TS were significantly lower in group C(5.09 ± 1.28) ms / R-R and group B(5.01±1.04)ms / R-R than in group A(8.39 ± 1.05)ms / R-R (all P < 0.01). Conclusion TO increases and TS decreases ob-viously and their changes are closely related to 24-hour urine protein measurements in type 2 DM patients.