中华妇幼临床医学杂志（电子版）
中華婦幼臨床醫學雜誌（電子版）
중화부유림상의학잡지（전자판）
CHINESE JOURNAL OF OBSTETRICS & GYNECOLOGY AND PEDIATRICS(ELECTRONIC VERSION)
2012年
4期
372-374
,共3页
郑迅风%董巨浪%杜继红%陈艳鸿
鄭迅風%董巨浪%杜繼紅%陳豔鴻
정신풍%동거랑%두계홍%진염홍
妊娠期糖尿病%饮食控制%运动%胰岛素%妊娠结局
妊娠期糖尿病%飲食控製%運動%胰島素%妊娠結跼
임신기당뇨병%음식공제%운동%이도소%임신결국
gestational diabetes mellitus%diet control%exercise%insulin%perinatal outcomes
目的 探讨妊娠期糖尿病(GDM)经干预治疗后对妊娠结局的影响.方法 选取2009年1月至2011年6月于本院门诊确诊为GDM的125例患者的临床病历资料为研究对象,纳入研究组.对其采取控制血糖的方法包括单纯饮食及运动干预与饮食及运动+胰岛素治疗.随机选择同期在本院住院分娩的125例血糖正常孕妇的临床病历资料纳入对照组.采用回顾性分析方法,比较两组孕妇一般情况、妊娠合并症发生情况及妊娠结局,并进行相关统计学处理(本研究遵循的程序符合本院人体试验委员会所制定的伦理学标准,得到该委员会批准,分组征得受试对象本人的知情同意,并与之签署临床研究知情同意书).结果 两组孕妇分娩前体重指数(BMI)、分娩孕周等比较,差异均无统计学意义(P＞0.05).研究组孕妇的年龄高于对照组,差异有统计学意义(P＜0.01).研究组患者经饮食及运动治疗后,血糖控制满意、病情稳定者共计93例(74.4％),妊娠结局良好;其余32例同时采用胰岛素治疗后,30例血糖控制良好,妊娠结局无特殊,另外2例血糖控制不满意孕妇,合并子痫前期,均于35～36孕周终止妊娠,在计划终止妊娠前48 h行羊膜腔穿刺术了解胎肺成熟情况,并羊膜腔内注入地塞米松促胎肺成熟.两组孕妇妊娠结局及母儿并发症发生情况比较,差异均无统计学意义(P＞0.05).结论 孕妇的年龄是GDM发病的高危因素之一.GDM患者经饮食及运动和及时合理的胰岛素治疗,有利于减少围生期并发症,改善妊娠结局.
目的 探討妊娠期糖尿病(GDM)經榦預治療後對妊娠結跼的影響.方法 選取2009年1月至2011年6月于本院門診確診為GDM的125例患者的臨床病歷資料為研究對象,納入研究組.對其採取控製血糖的方法包括單純飲食及運動榦預與飲食及運動+胰島素治療.隨機選擇同期在本院住院分娩的125例血糖正常孕婦的臨床病歷資料納入對照組.採用迴顧性分析方法,比較兩組孕婦一般情況、妊娠閤併癥髮生情況及妊娠結跼,併進行相關統計學處理(本研究遵循的程序符閤本院人體試驗委員會所製定的倫理學標準,得到該委員會批準,分組徵得受試對象本人的知情同意,併與之籤署臨床研究知情同意書).結果 兩組孕婦分娩前體重指數(BMI)、分娩孕週等比較,差異均無統計學意義(P＞0.05).研究組孕婦的年齡高于對照組,差異有統計學意義(P＜0.01).研究組患者經飲食及運動治療後,血糖控製滿意、病情穩定者共計93例(74.4％),妊娠結跼良好;其餘32例同時採用胰島素治療後,30例血糖控製良好,妊娠結跼無特殊,另外2例血糖控製不滿意孕婦,閤併子癇前期,均于35～36孕週終止妊娠,在計劃終止妊娠前48 h行羊膜腔穿刺術瞭解胎肺成熟情況,併羊膜腔內註入地塞米鬆促胎肺成熟.兩組孕婦妊娠結跼及母兒併髮癥髮生情況比較,差異均無統計學意義(P＞0.05).結論 孕婦的年齡是GDM髮病的高危因素之一.GDM患者經飲食及運動和及時閤理的胰島素治療,有利于減少圍生期併髮癥,改善妊娠結跼.
목적 탐토임신기당뇨병(GDM)경간예치료후대임신결국적영향.방법 선취2009년1월지2011년6월우본원문진학진위GDM적125례환자적림상병력자료위연구대상,납입연구조.대기채취공제혈당적방법포괄단순음식급운동간예여음식급운동+이도소치료.수궤선택동기재본원주원분면적125례혈당정상잉부적림상병력자료납입대조조.채용회고성분석방법,비교량조잉부일반정황、임신합병증발생정황급임신결국,병진행상관통계학처리(본연구준순적정서부합본원인체시험위원회소제정적윤리학표준,득도해위원회비준,분조정득수시대상본인적지정동의,병여지첨서림상연구지정동의서).결과 량조잉부분면전체중지수(BMI)、분면잉주등비교,차이균무통계학의의(P＞0.05).연구조잉부적년령고우대조조,차이유통계학의의(P＜0.01).연구조환자경음식급운동치료후,혈당공제만의、병정은정자공계93례(74.4％),임신결국량호;기여32례동시채용이도소치료후,30례혈당공제량호,임신결국무특수,령외2례혈당공제불만의잉부,합병자간전기,균우35～36잉주종지임신,재계화종지임신전48 h행양막강천자술료해태폐성숙정황,병양막강내주입지새미송촉태폐성숙.량조잉부임신결국급모인병발증발생정황비교,차이균무통계학의의(P＞0.05).결론 잉부적년령시GDM발병적고위인소지일.GDM환자경음식급운동화급시합리적이도소치료,유리우감소위생기병발증,개선임신결국.
Objective To study the effects of treatment on the pregnancy outcomes in gestational diabetes mellitus (GDM)women.Methods From January 2009 to June 2011,125 case of GDM women diagnosed at outpatient department were included in the study group.The methods of controlling blood glucose levels included diets control and exercises only,diets control and exercises + insulin therapy.Anather 125 cases with normal blood glucose who delivered in the same hospital were selected randomly as control group.The differences on gravid general situations and pregnancy outcomes between two groups were observed. Clinical data were restrospectively analyzed. Informed consent was obtained from all participants.Results There were no significant differences in body mass index(BMI) before delivery and gestational ages at delivery(P＞ 0.05),while there had significant difference in ages between two groups (P＜0.01).In study group,there were 93 cases (74.4％) who had been treated by diets control and exercises had satisfactory blood glucose levels and pregnancy outcomes; the other 32 cases who had been treated by insulin,Among them there were 30 cases had satisfactory blood glucose levels and pregnancy outcomes,only 2 cases whose blood glucose levels controlled unsatisfactorily and complicated with preeclampsia,were terminated pregnancy at 35 ～ 36 weeks.In order to evaluate fetal lung maturation,amniocentesis was performed before 48 h of termination,and dexamethasone was given in amniotic cavity for enhancement of fetal lung maturation.There were no significant differences in pregnancy outcomes,maternal and neonatal complications between two groups.Conclusions Maternal age is one of the high risk factors of GDM.Diets control,exercises,timely and properly use of insulin for GDM would reduce perinatal complications and improve perinatal outcomes.
