CAJ | 학술논문

目的通过与单光子发射计算机体层摄影术(SPECT)骨扫描对比,初步探讨全身MR扩散加权成像(DWI)技术探测骨转移灶的可行性.方法对42名正常志愿者及38例可疑合并骨转移的恶性肿瘤患者行全身MR DWI及SPECT骨扫描,并将骨骼系统分为8个区域,分别记录每例患者各区域全身MR DWI和SPECT骨扫描分别显示的病灶数目及各区域阳性病例数,进行每一患者及每一区域的全身MR DWI及骨扫描的对照分析.结果全身MR DWI阳性病例30例,受累区域69处,共探测出病灶数169处;骨扫描阳性病例29例,受累区域68处,共探测出病灶数156处;全身MR DWI阳性而SPECT骨扫描阴性者2例,SPECT骨扫描阳性而全身MR DWI阴性者1例;SPECT骨扫描阴性而全身MR DWI阳性区域8例,其中,脊柱3例、骨盆2例、股骨3例;骨扫描阳性而全身MRDWI阴性区域7例,其中颅骨4例、肩胛骨2例、胸锁骨1例.结论全身MR DWI与SPECT骨扫描对检测骨转移病灶有很好的一致性,且两者可互相补充;全身MR DWI还可检测各脏器及淋巴结病灶,适用于肿瘤患者随访.
목적 통과여단광자발사계산궤체층섭영술(SPECT)골소묘대비,초보탐토전신MR확산가권성상(DWI)기술탐측골전이조적가행성.방법 대42명정상지원자급38례가의합병골전이적악성종류환자행전신MR DWI급SPECT골소묘,병장골격계통분위8개구역,분별기록매례환자각구역전신MR DWI화SPECT골소묘분별현시적병조수목급각구역양성병례수,진행매일환자급매일구역적전신MR DWI급골소묘적대조분석.결과 전신MR DWI양성병례30례,수루구역69처,공탐측출병조수169처;골소묘양성병례29례,수루구역68처,공탐측출병조수156처;전신MR DWI양성이SPECT골소묘음성자2례,SPECT골소묘양성이전신MR DWI음성자1례;SPECT골소묘음성이전신MR DWI양성구역8례,기중,척주3례、골분2례、고골3례;골소묘양성이전신MRDWI음성구역7례,기중로골4례、견갑골2례、흉쇄골1례.결론 전신MR DWI여SPECT골소묘대검측골전이병조유흔호적일치성,차량자가호상보충;전신MR DWI환가검측각장기급림파결병조,괄용우종류환자수방.
0bjective To evaluate the application of whole body MR diffusion weighted imaging (DWI)in the detection of bone metastasis using skeletal scintigraphy as the referenee.Methods Fonv.two healthy volunteers and 38 patients with malignant tumors were enrolled in our studv.A11 the patients received MR examination and skeletal scintigraphy within one week.MR examination was performed on GE signa 3.0T MR scanner using a build.in body coil.The skeletal system Was divided into eight regons and the images of the whole body MR DWI and skeletal seintigraphy were reviewed to compare the two modalities patient by patient and region by region.The images were reviewed separately by two radiologists and two nuclear medicine physicians,who were blinded to the results of another imaging modality.Results A total of 169 metastatic lesions in 69 regions of 30 patients were detected by whole body MR DWI while 156 lesions in 68 regions of 29 patients were identified by skeletal seintigraphy.There were two cases negative in scintigraphy but positive in whole body MR DWI and one case positive in scintigraphy only.There were eight lesions negative in scintigraphy but positive in whole body MR DWI,mainly located in the spine.pelvis and femur.Seven 1esions were only detected by scintigraphy,mainly located in the skull.sternum.clavicle and scapula.Conclusion The whole body MR DWI reveals excellent consistency with skeletal scintigraphy regarding bone metastasis.and the two modalities are complementary for each Other.