国际医药卫生导报
國際醫藥衛生導報
국제의약위생도보
INTERNATIONAL MEDICINE & HEALTH GUIDANCE NEWS
2010年
16期
1931-1933
,共3页
范子文%廖壮文%杨进顺%黄文铎
範子文%廖壯文%楊進順%黃文鐸
범자문%료장문%양진순%황문탁
生物型椎间融合器%颈椎%异体骨%生物力学
生物型椎間融閤器%頸椎%異體骨%生物力學
생물형추간융합기%경추%이체골%생물역학
Biometerial fusion cages%Cervical spine%Allograft%Biomechanics
目的 研制一种新型的一体成型式皮质骨颈椎椎间融合器(forming one cortical biological cervical fusion cage,FOCBCFC)并探讨其生物力学性能.方法 从两具强壮青年男性的新鲜尸体上截取四段腓骨中段骨,按制特定形状和规格制成FOCBCFC并冻干,然后在生物力学实验机上进行力学破坏实验,了解融合器的压缩破坏载、压缩强度等生物力学性能,并将结果与文献报道进行比较分析.结果 该组FOCBCFC融合器的压缩破坏载荷为(4.451±0.270)KN,与ADFC(8.500±0.180)KN、纯钛TFC(5.860±0.380)KN及植骨块(2.080±0.190)的破坏载荷相比,统计学分析组间抗压力有明显的差异性(P<0.05),FOCBCFC的压缩破坏载荷介于植骨块与纯钛TFC和ADFC之间,优于植骨块.结论 FOCBCFC的设计符合颈椎椎间隙解剖学特点,具有足够的支撑、维持和增加椎间隙高度的作用,其生物力学性能可满足颈椎前路融合内固定术后近中期稳定性作用,符合临床应用要求.
目的 研製一種新型的一體成型式皮質骨頸椎椎間融閤器(forming one cortical biological cervical fusion cage,FOCBCFC)併探討其生物力學性能.方法 從兩具彊壯青年男性的新鮮尸體上截取四段腓骨中段骨,按製特定形狀和規格製成FOCBCFC併凍榦,然後在生物力學實驗機上進行力學破壞實驗,瞭解融閤器的壓縮破壞載、壓縮彊度等生物力學性能,併將結果與文獻報道進行比較分析.結果 該組FOCBCFC融閤器的壓縮破壞載荷為(4.451±0.270)KN,與ADFC(8.500±0.180)KN、純鈦TFC(5.860±0.380)KN及植骨塊(2.080±0.190)的破壞載荷相比,統計學分析組間抗壓力有明顯的差異性(P<0.05),FOCBCFC的壓縮破壞載荷介于植骨塊與純鈦TFC和ADFC之間,優于植骨塊.結論 FOCBCFC的設計符閤頸椎椎間隙解剖學特點,具有足夠的支撐、維持和增加椎間隙高度的作用,其生物力學性能可滿足頸椎前路融閤內固定術後近中期穩定性作用,符閤臨床應用要求.
목적 연제일충신형적일체성형식피질골경추추간융합기(forming one cortical biological cervical fusion cage,FOCBCFC)병탐토기생물역학성능.방법 종량구강장청년남성적신선시체상절취사단비골중단골,안제특정형상화규격제성FOCBCFC병동간,연후재생물역학실험궤상진행역학파배실험,료해융합기적압축파배재、압축강도등생물역학성능,병장결과여문헌보도진행비교분석.결과 해조FOCBCFC융합기적압축파배재하위(4.451±0.270)KN,여ADFC(8.500±0.180)KN、순태TFC(5.860±0.380)KN급식골괴(2.080±0.190)적파배재하상비,통계학분석조간항압력유명현적차이성(P<0.05),FOCBCFC적압축파배재하개우식골괴여순태TFC화ADFC지간,우우식골괴.결론 FOCBCFC적설계부합경추추간극해부학특점,구유족구적지탱、유지화증가추간극고도적작용,기생물역학성능가만족경추전로융합내고정술후근중기은정성작용,부합림상응용요구.
Objective To develop a novel cervical intervertebral body fusion cage - a biometerial cage, and to explore its biomechanics. Methods The fusion cage was made of an entire piece of fresh allograft cortical bone and cooled to try, having its specific shape and size.The magnitude of the load that the cage had to cany was measured by a Sweden biomechanical testing machine. The findings were compared with those from other medical literatures. Results The maximum load level of this biometerial cage was (5.860 ± 0.380)KN that was significantly different from that of the other cages using slices of autograph, tilium TFC, and ADFC(P<0.05). Conclusions The load that this biometerial cage can carry satisfies the need to support the initial stability of the reconstructed spinal column.