CAJ | 학술논문

目的观察特发性黄斑前膜的光相干断层扫描(OCT)特征以及与患者视力的相互关系.方法回顾分析2008年5月至12月间确诊的特发性黄斑前膜患者112例116只眼的临床资料.所有患者均进行最佳矫正视力、眼底和OCT检查.视力采用LogMAR视力表检查;眼底检查采用直接检眼镜和前置镜检查;OCT检查采用Zeiss HD-OCT,扫描速度27 000 A扫描/s,扫描区域6.0 mm× 6.0 mm,扫描模式为512×128.根据OCT检查所见的黄斑前膜对视网膜不同牵引情况对黄斑前膜进行分类,测量黄斑中心厚度(CFT)、体积、平均厚度以及黄斑中心凹厚度(FT).采用SPSS16.0软件对患者的各项OCT检查指标和临床检查结果进行统计分析. 结果 116只黄斑前膜眼可分为无视网膜牵引、切线方向或切线方向合并前后方向牵引3种情况,各自分别占本组患眼的9.48%、84.48%、6.04%.97只眼合并视网膜水肿,占总眼数的83.62%;水肿分别位于外核层(ONL),外网状层(OPL),内核层(INL).14只眼合并视网膜神经纤维层(RNFL)劈裂,占总眼数的12.07%;27只眼有视细胞内外节(IS/OS)损伤,占总眼数的23.28%.CFT与视力密切相关(P<0.05),而体积、平均厚度和FT与视力无相关性(P>0.05).患者年龄、性别、不同种类的视网膜牵引、是否合并板层孔、IS/OS损伤和RNFL劈裂等与视力无相关性.结论特发性黄斑前膜的OCT特征可表现为有无视网膜牵引以及视网膜水肿和视网膜神经纤维层劈裂.在CFT、体积、平均厚度以及FT等黄斑区OCT测量指标中,CFT与患者的视力关系最为密切.
목적 관찰특발성황반전막적광상간단층소묘(OCT)특정이급여환자시력적상호관계.방법 회고분석2008년5월지12월간학진적특발성황반전막환자112례116지안적림상자료.소유환자균진행최가교정시력、안저화OCT검사.시력채용LogMAR시력표검사;안저검사채용직접검안경화전치경검사;OCT검사채용Zeiss HD-OCT,소묘속도27 000 A소묘/s,소묘구역6.0 mm× 6.0 mm,소묘모식위512×128.근거OCT검사소견적황반전막대시망막불동견인정황대황반전막진행분류,측량황반중심후도(CFT)、체적、평균후도이급황반중심요후도(FT).채용SPSS16.0연건대환자적각항OCT검사지표화림상검사결과진행통계분석. 결과 116지황반전막안가분위무시망막견인、절선방향혹절선방향합병전후방향견인3충정황,각자분별점본조환안적9.48%、84.48%、6.04%.97지안합병시망막수종,점총안수적83.62%;수종분별위우외핵층(ONL),외망상층(OPL),내핵층(INL).14지안합병시망막신경섬유층(RNFL)벽렬,점총안수적12.07%;27지안유시세포내외절(IS/OS)손상,점총안수적23.28%.CFT여시력밀절상관(P<0.05),이체적、평균후도화FT여시력무상관성(P>0.05).환자년령、성별、불동충류적시망막견인、시부합병판층공、IS/OS손상화RNFL벽렬등여시력무상관성.결론 특발성황반전막적OCT특정가표현위유무시망막견인이급시망막수종화시망막신경섬유층벽렬.재CFT、체적、평균후도이급FT등황반구OCT측량지표중,CFT여환자적시력관계최위밀절.
Objective To observe the Fourier-domain optical coherence tomography(FD-OCT) characteristic of idiopathic epiretinal membrane (ERM) and its correlation with the patients visual acuity. Methods The 116 eyes (112 patients) with idiopathic epiretinal membrane were included in this study. All the patients had undergone examination of visual acuity (LogMAR chart), ocular fundus (direct ophthalmoscope and fundus pre-set lens), and FD-OCT (Zeiss HD-OCT) with the speed of 27 000 A scan/s, area of 6.0 mm× 6.0 mm, and mode of 512 × 128. The central fovea thickness (CFT), volume (V), average thickness (AT) were collected from the OCT readings, and the fovea thickness (FT) was measured manually. Data were analyzed using SPSS 16.0. Results The traction on retina caused by ERM can be divided into 3 types according to the OCT findings., no traction (9.48 %), tangential traction (84.48 %) and tangential traction with anterior-posterior traction (6.04 %). A total of 97 eyes (83.62 %) had retinal edema (diffuse or cystoid) and the edema located at the outer nuclear layer(ONL), outer plexiform layer(OPL)and inner nuclear layer (INL). A total of 14 eyes (12. 07%) had retinal nerve fiber layer (RNFL) schisis and 27 eyes (23.28%) had inner segment/outer segment j unction(Ls/OS) impairment. Statistic analysis revealed that BCVA was not related to the age, gender, types of traction, presence of IS/OS damage or RNFL schisis(P>0.05), but was related with CFT(P<0.05). Conclusions Idiopathic ERM can exert different types of traction on the macular, and cause different types of retinal lesions. OCT is a useful tool to measure these lesions. CFT reading is closely related to patients" visual acuity.