国际眼科杂志
國際眼科雜誌
국제안과잡지
INTERNATIONAL JOURNAL OF OPHTHALMOLOGY
2005年
2期
221-224
,共4页
肝细胞生长因子%酶联免疫吸附%增殖性玻璃体视网膜病变
肝細胞生長因子%酶聯免疫吸附%增殖性玻璃體視網膜病變
간세포생장인자%매련면역흡부%증식성파리체시망막병변
hepatocyte growth factor%enzyme-linked immunosorbent assay%proliferative vitreoretinopathy
目的:探讨肝细胞生长因子(hepatocyte growthfactor)在视网膜脱离后增殖性玻璃体视网膜病变(proliferative vitreoretinopathy,PVR)中的作用.方法:酶联免疫吸附法(enzyme-linked immuno-sorbent assay)测定49例视网膜脱离(retinal detachment)患者视网膜下液(subretinal fluid,SRF)中肝细胞生长因子的含量.结果:随着PVR程度及玻璃体混浊(vitreous opacity)的加重、病程的延长,肝细胞生长因子含量增加,P<0.05,差异有统计学意义.结论:SRF中肝细胞生长因子改变与视网膜脱离后PVR的发生、发展有密切关系.
目的:探討肝細胞生長因子(hepatocyte growthfactor)在視網膜脫離後增殖性玻璃體視網膜病變(proliferative vitreoretinopathy,PVR)中的作用.方法:酶聯免疫吸附法(enzyme-linked immuno-sorbent assay)測定49例視網膜脫離(retinal detachment)患者視網膜下液(subretinal fluid,SRF)中肝細胞生長因子的含量.結果:隨著PVR程度及玻璃體混濁(vitreous opacity)的加重、病程的延長,肝細胞生長因子含量增加,P<0.05,差異有統計學意義.結論:SRF中肝細胞生長因子改變與視網膜脫離後PVR的髮生、髮展有密切關繫.
목적:탐토간세포생장인자(hepatocyte growthfactor)재시망막탈리후증식성파리체시망막병변(proliferative vitreoretinopathy,PVR)중적작용.방법:매련면역흡부법(enzyme-linked immuno-sorbent assay)측정49례시망막탈리(retinal detachment)환자시망막하액(subretinal fluid,SRF)중간세포생장인자적함량.결과:수착PVR정도급파리체혼탁(vitreous opacity)적가중、병정적연장,간세포생장인자함량증가,P<0.05,차이유통계학의의.결론:SRF중간세포생장인자개변여시망막탈리후PVR적발생、발전유밀절관계.
● AIM: To explore the role that hepatocyte growth factor plays in proliferative vitreoretinopathy (PVR) after retinal detachment.● METHODS: The contents of hepatocyte growth factor in subretinal fluid (SRF) in 49 cases with retinal detachment were measured with enzyme-linked immunosorbent assay.● RESULTS: With the worsening of PVR and vitreous opacity and prolonging of disease course, the content of hepatocyte growth factor increased (P<0.05), the difference being statistically significant.● CONCLUSION: The change of hepatocyte growth factor in SRF had a close relation ship with the occurrence and development of PVR after retinal detachment.