CAJ | 학술논문

报道1例自身免疫性多腺体综合征Ⅲ型C.患者男,68岁,以胫前黏液性水肿半年就诊,曾有白癜风病史19年,10个月前出现甲状腺功能亢进症状和体征,多种抗甲状腺自身抗体明显升高,先后两次行放射性131I治疗后,甲状腺功能亢进症状明显改善.患者就诊时表情淡漠、突眼,胫前片状肿胀、增厚、呈橘皮样改变,躯干四肢多处色素脱失斑.白癜风常与多种自身免疫性疾病伴发,自身免疫在其发病中起了重要的作用,临床工作中应引起重视.
보도1례자신면역성다선체종합정Ⅲ형C.환자남,68세,이경전점액성수종반년취진,증유백전풍병사19년,10개월전출현갑상선공능항진증상화체정,다충항갑상선자신항체명현승고,선후량차행방사성131I치료후,갑상선공능항진증상명현개선.환자취진시표정담막、돌안,경전편상종창、증후、정귤피양개변,구간사지다처색소탈실반.백전풍상여다충자신면역성질병반발,자신면역재기발병중기료중요적작용,림상공작중응인기중시.
A case of autoimmune polyglandular syndrome-3C is reported.A 68-year-old male presented with a half-year history of pretibial myxedema and a 19-year history of vitiligo.Ten months prior to the presentation,the patient developed symptoms and signs of hyperthyroidism with the increase of multiple antithyroid autoantibody levels.After two sessions of treatment with radioiodine (131I),the symptoms and signs of hyperthyroidism markedly improved.On admission,the patient presented with indifferent expression,exophthalmos,bilateral pretibial swelling which gave an orange peel-like appearance,and many hypopigmented patches on the trunk and extremities.Autoimmunity exerts essential role in the pathogenesis of vitiligo which is often accompanied by many other autoimmune diseases.More attention should be given to this phenomenon in clinic.