国际医药卫生导报
國際醫藥衛生導報
국제의약위생도보
INTERNATIONAL MEDICINE & HEALTH GUIDANCE NEWS
2010年
23期
2909-2913
,共5页
积雪草总苷缓释片%含量测定%稳定性
積雪草總苷緩釋片%含量測定%穩定性
적설초총감완석편%함량측정%은정성
Centella asiatica glycosides extract tablets%Content assay%Stability
目的 积雪草总苷缓释片的含量测定及制剂稳定性考察.方法 利用反相高效液相色谱法测定羟基积雪草苷和积雪草苷的含量;通过影响因素实验、加速实验和长期实验进行初步稳定性考察.结果 采用含量测定方法准确可靠,能较好控制积雪草总苷缓释片的质量;稳定性考察确定该制剂质量比较稳定.结论 积雪草总苷缓释片含量测定方法合适及该制剂较稳定.
目的 積雪草總苷緩釋片的含量測定及製劑穩定性攷察.方法 利用反相高效液相色譜法測定羥基積雪草苷和積雪草苷的含量;通過影響因素實驗、加速實驗和長期實驗進行初步穩定性攷察.結果 採用含量測定方法準確可靠,能較好控製積雪草總苷緩釋片的質量;穩定性攷察確定該製劑質量比較穩定.結論 積雪草總苷緩釋片含量測定方法閤適及該製劑較穩定.
목적 적설초총감완석편적함량측정급제제은정성고찰.방법 이용반상고효액상색보법측정간기적설초감화적설초감적함량;통과영향인소실험、가속실험화장기실험진행초보은정성고찰.결과 채용함량측정방법준학가고,능교호공제적설초총감완석편적질량;은정성고찰학정해제제질량비교은정.결론 적설초총감완석편함량측정방법합괄급해제제교은정.
Objective Study on content assay and preparation stability of Centella asiatica glycosides extract tablets for sustained release. Methods The madecasaoside and asiaticoside were assayed by RP-HPLC. The stability was inspected by influence factors test, accelerated sheff life test and long term storage test. Results The content assay method was accurate and reliable, good for quality control of the Centella asiatica glycosides extract tablets for sustained release, and the stability of the preparation was fine.Conclusion The content assay method was suitable for the preparation and the preparation was stable.
