CAJ | 학술논문

白色念珠菌等真菌是能够引起人类及动物患病的重要致病菌,测定了白鲜碱对临床22株临床分离氟康唑耐药白色念珠菌的最小抑菌浓度(MIC),采用棋盘式微量稀释试验测定了两药联合应药的分级抑制浓度指数(factional inhibitory concentration index,FICI)值.结果表明,白鲜碱有较好的抗白色念珠菌活性且与氟康唑有协同作用.
백색념주균등진균시능구인기인류급동물환병적중요치병균,측정료백선감대림상22주림상분리불강서내약백색념주균적최소억균농도(MIC),채용기반식미량희석시험측정료량약연합응약적분급억제농도지수(factional inhibitory concentration index,FICI)치.결과표명,백선감유교호적항백색념주균활성차여불강서유협동작용.
Candida albicans (C. albicans) and other fungi important human and veterinary pathogens. The minimal inhibitory concentration (MIC) of dictamnine alone and in combination with fluconazole (FLC) against clinical 22 clinical Candida albicans were tested, and checkerboard assay was used to analyze the ractional inhibitory concentration index (FICI) of the combination of dictamnine and FLC. The result showed that dictamnine had good antifungal activity alone and in combination with FLC against Candida albicans.