CAJ | 학술논문

目的探讨超高频超声在2型糖尿病患者腓肠神经损伤中的应用价值.方法选取有神经症状的糖尿病组、无神经症状糖尿病组和正常对照组的腓肠神经,分别为56条、64条和60条.应用22 MHz超高频超声测量并比较各组神经形态学指标,包括截面积(CSA)、厚/宽比(T/W ratio)以及最粗的神经束厚度(MT)等.结果 ①超声在各组中均可清晰显示腓肠神经的神经外膜、神经束膜和神经束等结构.②对照组、无症状组和症状组的T/W ratio和MT均依次增高,差异具有统计学意义(P＜0.05),CSA在三组间差异无统计学意义(P=0.257).结论超高频超声可显示糖尿病患者的腓肠神经形态学特征,有望为糖尿病皮神经损伤提供一种新的形态学评价工具.
목적 탐토초고빈초성재2형당뇨병환자비장신경손상중적응용개치.방법 선취유신경증상적당뇨병조、무신경증상당뇨병조화정상대조조적비장신경,분별위56조、64조화60조.응용22 MHz초고빈초성측량병비교각조신경형태학지표,포괄절면적(CSA)、후/관비(T/W ratio)이급최조적신경속후도(MT)등.결과 ①초성재각조중균가청석현시비장신경적신경외막、신경속막화신경속등결구.②대조조、무증상조화증상조적T/W ratio화MT균의차증고,차이구유통계학의의(P＜0.05),CSA재삼조간차이무통계학의의(P=0.257).결론 초고빈초성가현시당뇨병환자적비장신경형태학특정,유망위당뇨병피신경손상제공일충신적형태학평개공구.
Objective To evaluate the morphological changes of sural nerve in patients with type 2 diabetes mellitus by hyperfrequency ultrasound.Methods Fifty-six sural nerves of symptomatic group,64 sural nerves of asymptomatic group,and 60 sural nerves of control group were identified by 22 MHz Ultrasound.The thickness/width (T/W) ratio,cross-sectional areas (CSA) and the maximum thickness of neuronal fascicles (MT) of the sural nerve were calculated in transverse sonograms.Results ①Ultrasound can clearly show these structures of sural nerve such as epineurium,perineurium and nerve bundles and so on.②In symptomatic group,asymptomatic group and control group,T/W ratio and MT were gradually increased,and the differences among the three groups were statistically significant (P＜0.05).Whereas,there were no statistically significant differences in CSA among the three groups (P=0.257).Conclusions22 MHz ultrasound may be a valuable tool in evaluating the diabetic cutaneous nerve neuropathy