中华创伤骨科杂志
中華創傷骨科雜誌
중화창상골과잡지
CHINESE JOURNAL OF ORTHOPAEDIC TRAUMA
2010年
3期
217-220
,共4页
脑损伤%骨折%四肢%雌激素%血清
腦損傷%骨摺%四肢%雌激素%血清
뇌손상%골절%사지%자격소%혈청
Brain injuries%Fractures%Extremities%Estrogens%Serum
目的 观察青年女性脑外伤合并四肢长管状骨骨折患者伤后不同时间段血清雌二醇(E2)及泌乳素(PRL)水平的变化.方法 2007年1月至2008年12月,对39例青年女性脑外伤合并四肢长管状骨骨折患者(观察组)和42例青年女性单纯四肢长管状骨骨折患者(对照组)均于伤后1～3 d、5～7 d、10～14 d、28～30 d和56～60 d时间段进行血清中E2和PRL浓度测定和比较. 结果 血清E2浓度比较中,观察组1～3 d、5～7d、10～14 d和28～30 d均明显高于对照组同期检测 结果 ,差异均有统计学意义(P<0.05);而56～60 d时间段两组差异无统计学意义(P>0.05);观察组其他时间段均明显低于1～3 d检测 结果 ,差异均有统计学意义(P<0.05),对照组各时间段间比较差异均无统计学意义(P>0.05).血清PRL浓度比较中,观察组全部时间段均明显高于对照组同期检测 结果 ,差异有统计学意义(P<0.05);观察组5～7 d、10～14 d和28～30 d时间段均明显高于1～3 d检测 结果 ,差异均有统计学意义(P<0.05);而56～60 d与1～3 d时间段比较差异无统计学意义(P>0.05);对照组各时间段间比较差异均无统计学意义(P>0.05).观察组的骨折愈合时间明显短于对照组,而前者住院总时间明显长于后者,差异均有统计学意义(P<0.05). 结论 青年女性脑外伤合并四肢长管状骨骨折的患者伤后早期E2和PRL水平明显升高.
目的 觀察青年女性腦外傷閤併四肢長管狀骨骨摺患者傷後不同時間段血清雌二醇(E2)及泌乳素(PRL)水平的變化.方法 2007年1月至2008年12月,對39例青年女性腦外傷閤併四肢長管狀骨骨摺患者(觀察組)和42例青年女性單純四肢長管狀骨骨摺患者(對照組)均于傷後1～3 d、5～7 d、10～14 d、28～30 d和56～60 d時間段進行血清中E2和PRL濃度測定和比較. 結果 血清E2濃度比較中,觀察組1～3 d、5～7d、10～14 d和28～30 d均明顯高于對照組同期檢測 結果 ,差異均有統計學意義(P<0.05);而56～60 d時間段兩組差異無統計學意義(P>0.05);觀察組其他時間段均明顯低于1～3 d檢測 結果 ,差異均有統計學意義(P<0.05),對照組各時間段間比較差異均無統計學意義(P>0.05).血清PRL濃度比較中,觀察組全部時間段均明顯高于對照組同期檢測 結果 ,差異有統計學意義(P<0.05);觀察組5～7 d、10～14 d和28～30 d時間段均明顯高于1～3 d檢測 結果 ,差異均有統計學意義(P<0.05);而56～60 d與1～3 d時間段比較差異無統計學意義(P>0.05);對照組各時間段間比較差異均無統計學意義(P>0.05).觀察組的骨摺愈閤時間明顯短于對照組,而前者住院總時間明顯長于後者,差異均有統計學意義(P<0.05). 結論 青年女性腦外傷閤併四肢長管狀骨骨摺的患者傷後早期E2和PRL水平明顯升高.
목적 관찰청년녀성뇌외상합병사지장관상골골절환자상후불동시간단혈청자이순(E2)급비유소(PRL)수평적변화.방법 2007년1월지2008년12월,대39례청년녀성뇌외상합병사지장관상골골절환자(관찰조)화42례청년녀성단순사지장관상골골절환자(대조조)균우상후1～3 d、5～7 d、10～14 d、28～30 d화56～60 d시간단진행혈청중E2화PRL농도측정화비교. 결과 혈청E2농도비교중,관찰조1～3 d、5～7d、10～14 d화28～30 d균명현고우대조조동기검측 결과 ,차이균유통계학의의(P<0.05);이56～60 d시간단량조차이무통계학의의(P>0.05);관찰조기타시간단균명현저우1～3 d검측 결과 ,차이균유통계학의의(P<0.05),대조조각시간단간비교차이균무통계학의의(P>0.05).혈청PRL농도비교중,관찰조전부시간단균명현고우대조조동기검측 결과 ,차이유통계학의의(P<0.05);관찰조5～7 d、10～14 d화28～30 d시간단균명현고우1～3 d검측 결과 ,차이균유통계학의의(P<0.05);이56～60 d여1～3 d시간단비교차이무통계학의의(P>0.05);대조조각시간단간비교차이균무통계학의의(P>0.05).관찰조적골절유합시간명현단우대조조,이전자주원총시간명현장우후자,차이균유통계학의의(P<0.05). 결론 청년녀성뇌외상합병사지장관상골골절적환자상후조기E2화PRL수평명현승고.
Objective To investigate the estradiol (E2) prolactin (PRL) levels in young females with cerebral trauma combined with extremity long tubular bone fracture. Methods E2 and PRL were detected in 39 young females with cerebral trauma combined with extremity long tubular bone fracture (experimental group) and 42 young females with just extremity long tubular bone fracture (control group) at 1 to 3, 5 to 7, 10 to 14, 28 to 30, and 56 to 60 days after injury. Results E2 levels in the experimental group were significantly higher than in the control group at 1 to 3, 5 to 7, 10 to 14, and 28 to 30 days after injury (P < 0.05), but there was no significant difference in the E2 level between the 2 groups at 56 to 60 days after injury (P > 0.05) . Compared with 1 to 3 days, the E2 level was significantly decreased in the experimental group at other time points (P < 0. 05), while there was no significant difference in the E2 level in the control group among each time point (P > 0. 05). PRL level in the experimental group was significantly higher than in the control group at all time points. In particular, the PRL level in the experimental group was significantly increased at 5 to 7, 10 to 14 and 28 to 30 days after injury, compared with that at 1 to 3 days after injury (P<0.05), but there was no significant difference in the PRL level between 56 to 60 days and 1 to 3 days (P > 0. 05). Additionally, the PRL level did not change in the control group at all time points (P > 0.05). Time of fracture healing in the experimental group was significantly shorter than in the control group, while the time of hospital stay in the experimental group was significantly longer than in the control group (P<0.05). Conclusion E2 and PRL levels increase remarkably in the young females with cerebral trauma combined with extremity long tubular bone fracture at an early onset stage.
