CAJ | 학술논문

[目的]分析高血压病合并冠心病患者的中心动脉血压参数和冠状动脉粥样硬化病变的关系.[方法]连续选取高血压病合并冠心病患者155例,分为单支病变组、双支病变组、三支病变组,通过无创和有创的方法测量患者肱动脉血压、升主动脉血压.分析血压参数和冠状动脉病变的关系.[结果]单支病变组、双支病变组、三支病变组外周动脉收缩压(SBP)、脉压(PP)和中心动脉SBP、PP、收缩压分数[FSP=SBP/平均动脉压(MAP)]随冠状动脉病变支数的增加而增加,中心动脉舒张压分数(FDP=DBP/MAP)随冠状动脉病变支数的增加而降低(P均＜0.05).中心动脉FSP、PP的升高以及FDP的降低是冠心病三支病变的危险因素.[结论]高血压病患者的中心动脉压可预测冠状动脉硬化程度.
[목적]분석고혈압병합병관심병환자적중심동맥혈압삼수화관상동맥죽양경화병변적관계.[방법]련속선취고혈압병합병관심병환자155례,분위단지병변조、쌍지병변조、삼지병변조,통과무창화유창적방법측량환자굉동맥혈압、승주동맥혈압.분석혈압삼수화관상동맥병변적관계.[결과]단지병변조、쌍지병변조、삼지병변조외주동맥수축압(SBP)、맥압(PP)화중심동맥SBP、PP、수축압분수[FSP=SBP/평균동맥압(MAP)]수관상동맥병변지수적증가이증가,중심동맥서장압분수(FDP=DBP/MAP)수관상동맥병변지수적증가이강저(P균＜0.05).중심동맥FSP、PP적승고이급FDP적강저시관심병삼지병변적위험인소.[결론]고혈압병환자적중심동맥압가예측관상동맥경화정도.
[Objective]To analyze the relationship between central arterial blood pressure and extent of coronary arterial atherosclerosis in patients with essential hypertension.[Methods]The study consisted of 155 patients with essential hypertension and coronary artery disease.Their brachial blood pressure was measured by Mercury sphygmomanometer and central arterial blood pressure by 6F JR catheter.The number of diseased vessels were counted.The patients were categorized into:one-vessel,two-vessels and three-vessels coronary artery disease group.Central aortic SBP and DBP was measured by cathetarization during angiography of coronary artery and brachial blood pressure was measured using cuff method.The relationship between blood pressure and coronary artery disease was analyzed.[Results]Peripheral SBP,PP and ascending aortic SBP,PP,fractional systolic pressure(FSP=SBP/MAP) were increased and ascending aortic fractional diastolic pressure(FDP=DBP/MAP) was reduced when the diseased coronary vessels were increased (P＜0.05).Multivariable logistic analysis showed:increased ascending aortic PP,FSP,and reduced FDP were prediposed risk factors of three-vessels coronary arterydisease.[Conclusions]Central arterial blood pressure measured by catheter in patients with essential hypertension can predict the extent of coronary arterial atherosclerosis.