肿瘤研究与临床
腫瘤研究與臨床
종류연구여림상
CANCER RESEARCH AND CLINIC
2009年
12期
793-795
,共3页
肿瘤标记%生物学%本-周蛋白%联合检测
腫瘤標記%生物學%本-週蛋白%聯閤檢測
종류표기%생물학%본-주단백%연합검측
Tumor marker%biological%Bence jones protein%Combined detection
自从1846年本-周蛋白(Bence-Jones Protein)被发现并应用于多发性骨髓瘤的诊断和治疗以来,众多后续发现的肿瘤标志物在恶性肿瘤的发现和治疗监测中发挥着重要作用.然而,目前已发现的大部分肿瘤标志物都因其特异性和(或)灵敏性不高而在应用中受限,肿瘤标志物联合检测和临床-肿瘤标志物综合评价可弥补肿瘤标志物单方面评价的不足,这也许是未来肿瘤标志物研究的方向.
自從1846年本-週蛋白(Bence-Jones Protein)被髮現併應用于多髮性骨髓瘤的診斷和治療以來,衆多後續髮現的腫瘤標誌物在噁性腫瘤的髮現和治療鑑測中髮揮著重要作用.然而,目前已髮現的大部分腫瘤標誌物都因其特異性和(或)靈敏性不高而在應用中受限,腫瘤標誌物聯閤檢測和臨床-腫瘤標誌物綜閤評價可瀰補腫瘤標誌物單方麵評價的不足,這也許是未來腫瘤標誌物研究的方嚮.
자종1846년본-주단백(Bence-Jones Protein)피발현병응용우다발성골수류적진단화치료이래,음다후속발현적종류표지물재악성종류적발현화치료감측중발휘착중요작용.연이,목전이발현적대부분종류표지물도인기특이성화(혹)령민성불고이재응용중수한,종류표지물연합검측화림상-종류표지물종합평개가미보종류표지물단방면평개적불족,저야허시미래종류표지물연구적방향.
Since Bence-Jones protein was discovered and used in multiple myeloma, many tumor markers have been used in diagnosis and treatment monitoring of various cancers. However the lack of specificity and sensitivity of most tumor markers is always limiting their application in research and clinical diagnosis currently. It is predicted that the future development of tumor marker research may mainly focus on the innovation of research strategies, such as combined detection of a set of related tumors marker and comprehensive interpretation of testing results.
