CAJ | 학술논문

目的比较赖脯胰岛素联合甘精胰岛素与胰岛素泵在2型糖尿病强化治疗中的疗效和安全性.方法将2型糖尿病病人随机分成两组,A组的病人采用三餐前赖脯胰岛素联合甘精胰岛素治疗,B组的病人采用胰岛素泵(使用赖脯胰岛素)降糖治疗.监测两组病人治疗前后全天血糖谱的变化,观察并比较血糖达标所需要的时间、胰岛素用量、低血糖发生率等情况.结果 A组与B组相比,在血糖达标所需的时间、胰岛素用量及低血糖发生率等方面没有显著性差异(P>0.05).结论赖脯胰岛素联合甘精胰岛素治疗2型糖尿病患者,在疗效、安全性方面接近胰岛素泵,在治疗费用方面则具有一定的优势.
목적 비교뢰포이도소연합감정이도소여이도소빙재2형당뇨병강화치료중적료효화안전성.방법 장2형당뇨병병인수궤분성량조,A조적병인채용삼찬전뢰포이도소연합감정이도소치료,B조적병인채용이도소빙(사용뢰포이도소)강당치료.감측량조병인치료전후전천혈당보적변화,관찰병비교혈당체표소수요적시간、이도소용량、저혈당발생솔등정황.결과 A조여B조상비,재혈당체표소수적시간、이도소용량급저혈당발생솔등방면몰유현저성차이(P>0.05).결론 뢰포이도소연합감정이도소치료2형당뇨병환자,재료효、안전성방면접근이도소빙,재치료비용방면칙구유일정적우세.
Objective Comparing efficacy and safety between insulin lispro combined with insulin glargine and insulin pump in the intensified therapy of patients with type 2 diabetes. Methods The patients with type 2 diabetic were randomly divided into two groups. The patients in group A were given insulin lispro combined with insulin glargine before meals, and the patients in group B received insulin pump therapy by infusing insulin lispro. The changes of blood glucose spectrum in two groups were monitored before and after treatment the whole day, and the time and the insulin dosage of glucose up to grade, incidence of hypoglycemia and so on in two groups were observed and compared. Results There were no significant differences in the time and the insulin dosage of glucose up to grade, the incidence of hypoglycemia and so on between two groups (P>0.05). Conclusion The curative effect and safety of insulin lispro combined with insulin glargine on patients with type 2 diabetes were close to those of insulin pump, while has a certain advantage in treatment costs.