CAJ | 학술논문

目的探讨年龄、肥胖、Epworth嗜睡量表(Epworth sleepiness score,ESS)评分等指标与鼾症和阻塞性睡眠呼吸暂停低通气综合征(obstructive sleep apnea hypopnea syndrome,OSAHS)发病及严重程度的相关关系.方法对2008年5～7月因睡眠时打鼾就诊的148名患者进行问卷调查和主观评分,进行至少1次的夜间多导睡眠图监测(polysomonography,PSG),并记录身高、体重,计算体重指数(BMI).年龄、BMI、最低SaO_2(%)、ESS评分、最大氧减(%)、总暂停时间、平均呼吸紊乱指数(respiratory disorder index,RDI)之间相关关系应用Pearson correlation检验计算;单纯鼾症组及OSAHS轻、中、重各组间比较采用广义线性模型分析.结果 OSAHS患者中比例男性高于女性,随年龄增长发生率呈递增趋势.ESS评分、BMI、最低SaO_2与RDI在统计学上有非常显著的相关关系,且以上因素与OSAHS的严重程度亦有明显的相关关系(P<0.05).结论 OSAHS在打鼾就诊人群中患病率高,年龄、肥胖是易患因素.BMI、ESS评分、最低SaO_2与RDI有良好的相关性,临床上可作为初步判断OSAHS患者病情的指标.
목적 탐토년령、비반、Epworth기수량표(Epworth sleepiness score,ESS)평분등지표여한증화조새성수면호흡잠정저통기종합정(obstructive sleep apnea hypopnea syndrome,OSAHS)발병급엄중정도적상관관계.방법 대2008년5～7월인수면시타한취진적148명환자진행문권조사화주관평분,진행지소1차적야간다도수면도감측(polysomonography,PSG),병기록신고、체중,계산체중지수(BMI).년령、BMI、최저SaO_2(%)、ESS평분、최대양감(%)、총잠정시간、평균호흡문란지수(respiratory disorder index,RDI)지간상관관계응용Pearson correlation검험계산;단순한증조급OSAHS경、중、중각조간비교채용엄의선성모형분석.결과 OSAHS환자중비례남성고우녀성,수년령증장발생솔정체증추세.ESS평분、BMI、최저SaO_2여RDI재통계학상유비상현저적상관관계,차이상인소여OSAHS적엄중정도역유명현적상관관계(P<0.05).결론 OSAHS재타한취진인군중환병솔고,년령、비반시역환인소.BMI、ESS평분、최저SaO_2여RDI유량호적상관성,림상상가작위초보판단OSAHS환자병정적지표.
Objective To investigate the possible correlation of the clinical parameters, such as age, obesity, Epworth sleepiness score (ESS), with the severity of snoring and obstructive sleep apnea hypopnea syndrome (OSAHS). Methods One hundred and forty-eight patients with snoring during sleep admitted from May to Jul. 2008 were asked to answer the questions from a questionnaire concerning snoring, daytime sleepiness, and habits such as smoking and drinking, etc. All patients underwent at least a polysomnography (PSG) and the physical examination included height, weight, and body mass index (BMI). Age, BMI, the lowest SaO_2(%), ESS score, the biggest reduction of oxygen (%), a total suspension of time, the average correlation between respiratory disorder index (RDI) applied computing Pearson correlation test. Simple snoring and OSAHS group of mild, moderate and severe inter-group comparison analysis using generalized linear models. Results The prevalence of OSAHS was increased with age, higher in males than in females. A statistically significant correlation between ESS, BMI, the lowest SaO_2 with the RDI was detected. The difference of ESS, the lowest SaO_2 and the BMI was significant between the different serious patients (P<0.05). Conclusions OSAHS has a high morbidity rate in outpatients with snoring. Age and obesity are liability factors of OSAHS. BMI, the lowest SaO_2, ESS and RDI have well correlationship, which can be used to assess the pathogenetic condition, even make a primary diagnosis.