国际脑血管病杂志
國際腦血管病雜誌
국제뇌혈관병잡지
INTERNATIONAL JOURNAL OF CEREBROVASCULAR DISEASES
2011年
6期
466-470
,共5页
S100蛋白质类%脑缺血%卒中%生物学标记
S100蛋白質類%腦缺血%卒中%生物學標記
S100단백질류%뇌결혈%졸중%생물학표기
S100 proteins%Brain ischemia%Stroke%Biological markers
S100B是一类酸性钙结合蛋白,在中枢神经系统中主要存在于胶质细胞,是星形胶质细胞活化的标志之一.S100B可反映胶质细胞的功能,调节神经元与胶质细胞之间复杂的相互作用.近年来的研究显示,S100B蛋白参与了急性缺血性脑损伤的病理学过程,血清S100B蛋白可作为预测脑梗死严重程度、进展以及转归的标记物.
S100B是一類痠性鈣結閤蛋白,在中樞神經繫統中主要存在于膠質細胞,是星形膠質細胞活化的標誌之一.S100B可反映膠質細胞的功能,調節神經元與膠質細胞之間複雜的相互作用.近年來的研究顯示,S100B蛋白參與瞭急性缺血性腦損傷的病理學過程,血清S100B蛋白可作為預測腦梗死嚴重程度、進展以及轉歸的標記物.
S100B시일류산성개결합단백,재중추신경계통중주요존재우효질세포,시성형효질세포활화적표지지일.S100B가반영효질세포적공능,조절신경원여효질세포지간복잡적상호작용.근년래적연구현시,S100B단백삼여료급성결혈성뇌손상적병이학과정,혈청S100B단백가작위예측뇌경사엄중정도、진전이급전귀적표기물.
S100B is a class of acid calcium-binding protein. It mainly exists in neuroglial cells in the central nervous system, and it is one of the signs of astrocyte activation. S100B may reflect the function of neuroglial cells and regulate the complex interactions between the neurons and neuroglial cells. Studies in recent years have demonstrated that S100B protein is involved in the pathological processes of acute ischemic brain injury. Serum S100B protein can be used as an important marker for identifying the severity of cerebral infarction, progress and outcome.