中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2010年
16期
2194-2195
,共2页
酒精中毒%纳洛酮%山莨菪碱
酒精中毒%納洛酮%山莨菪堿
주정중독%납락동%산랑탕감
Alcoholism%Naloxone%Anisodamine
目的 观察纳洛酮联合山莨菪碱治疗急性酒精中毒的临床疗效. 方法 78例急性酒精中毒患者按入院单双号随机分为对照组(35例)和治疗组(43例),对照组采用纳洛酮治疗,治疗组采用纳洛酮联合山莨菪碱治疗,比较两组临床治疗效果及不良反应发生情况. 结果 两组经治疗后症状均得到缓解,治疗组起效时间(12.8±6.1)min、症状减轻时间(32.4±8.7)min、症状消失时间(5.8±2.6)h,明显短于对照组的(15.7±5.5)min、(41.7±6.9)min、(7.1±3.1)h(t=3.64、4.01、3.52,均P＜0.05);两组均未发生严重不良反应. 结论 纳洛酮联合山莨菪碱治疗急性酒精中毒可显著缩短酒精中毒持续时间,起到更好的治疗效果.
目的 觀察納洛酮聯閤山莨菪堿治療急性酒精中毒的臨床療效. 方法 78例急性酒精中毒患者按入院單雙號隨機分為對照組(35例)和治療組(43例),對照組採用納洛酮治療,治療組採用納洛酮聯閤山莨菪堿治療,比較兩組臨床治療效果及不良反應髮生情況. 結果 兩組經治療後癥狀均得到緩解,治療組起效時間(12.8±6.1)min、癥狀減輕時間(32.4±8.7)min、癥狀消失時間(5.8±2.6)h,明顯短于對照組的(15.7±5.5)min、(41.7±6.9)min、(7.1±3.1)h(t=3.64、4.01、3.52,均P＜0.05);兩組均未髮生嚴重不良反應. 結論 納洛酮聯閤山莨菪堿治療急性酒精中毒可顯著縮短酒精中毒持續時間,起到更好的治療效果.
목적 관찰납락동연합산랑탕감치료급성주정중독적림상료효. 방법 78례급성주정중독환자안입원단쌍호수궤분위대조조(35례)화치료조(43례),대조조채용납락동치료,치료조채용납락동연합산랑탕감치료,비교량조림상치료효과급불량반응발생정황. 결과 량조경치료후증상균득도완해,치료조기효시간(12.8±6.1)min、증상감경시간(32.4±8.7)min、증상소실시간(5.8±2.6)h,명현단우대조조적(15.7±5.5)min、(41.7±6.9)min、(7.1±3.1)h(t=3.64、4.01、3.52,균P＜0.05);량조균미발생엄중불량반응. 결론 납락동연합산랑탕감치료급성주정중독가현저축단주정중독지속시간,기도경호적치료효과.
Objective To observe the curative effect of naloxone and anisodamine in the therapy of acute alcoholism. Methods 78 patients with acute alcoholism were randomly divided into control group(35 patients treated with naloxone)and treatment group(43 patients treated with naloxone combination with anisodamine).The curative effects were observed in the two groups. Results The symptoms were relieved and disappeared in the two groups.The effects began quickly in the treatment group than that in control group.The symptomatic relief time and extinction time in the treatment group were significantly shorter than that in the control group(t=3.64,4.01,3.52,all P <0.05).Conclusiou Naloxone combination with anisodamine could significantly shorten the endurance time of alcoholism.It might be a useful method in the therapy of acute alcoholism.
