国际内分泌代谢杂志
國際內分泌代謝雜誌
국제내분비대사잡지
INTERNATIONAL JOURNAL OF ENDOCRINOLOGY AND METABOLISM
2010年
3期
195-198
,共4页
葡萄糖调节受损%胰岛素抵抗%胰岛β细胞%代谢综合征%动脉粥样硬化
葡萄糖調節受損%胰島素牴抗%胰島β細胞%代謝綜閤徵%動脈粥樣硬化
포도당조절수손%이도소저항%이도β세포%대사종합정%동맥죽양경화
Impaired glucose regulation%Insulin resistance%Islet β cell%Metabolic syndrome%Atherosclerosis
葡萄糖调节受损(IGR)是介于正常血糖与糖尿病之间的一种中间状态.它同样具有2型糖尿病的两大基本特征:胰岛素抵抗和β细胞分泌功能受损.但它包括的两种血糖异常状态即空腹血糖受损和糖耐量减低具有不同的胰岛素抵抗和β细胞分泌功能特征及流行病学特征.我国普通成年人中15.5%发生IGR.IGR独立于代谢综合征的其他组分而与动脉粥样硬化性心血管疾病密切相关,采取生活方式及适当药物早期干预IGR可有效防治糖尿病及心血管疾病的发生.
葡萄糖調節受損(IGR)是介于正常血糖與糖尿病之間的一種中間狀態.它同樣具有2型糖尿病的兩大基本特徵:胰島素牴抗和β細胞分泌功能受損.但它包括的兩種血糖異常狀態即空腹血糖受損和糖耐量減低具有不同的胰島素牴抗和β細胞分泌功能特徵及流行病學特徵.我國普通成年人中15.5%髮生IGR.IGR獨立于代謝綜閤徵的其他組分而與動脈粥樣硬化性心血管疾病密切相關,採取生活方式及適噹藥物早期榦預IGR可有效防治糖尿病及心血管疾病的髮生.
포도당조절수손(IGR)시개우정상혈당여당뇨병지간적일충중간상태.타동양구유2형당뇨병적량대기본특정:이도소저항화β세포분비공능수손.단타포괄적량충혈당이상상태즉공복혈당수손화당내량감저구유불동적이도소저항화β세포분비공능특정급류행병학특정.아국보통성년인중15.5%발생IGR.IGR독립우대사종합정적기타조분이여동맥죽양경화성심혈관질병밀절상관,채취생활방식급괄당약물조기간예IGR가유효방치당뇨병급심혈관질병적발생.
Impaired glucose regulation (IGR) is a condition between normal blood glucose and diabetes mellitus. IGR also has two basic features of type 2 diabetes mellilus: insulin resistance and islet β cell dysfunction. On the other hand, IGR includes two different abnormal glycetnia conditions-impaired fasting glucose (IFG) and impaired glucose tolerance (IGT), which have distinct degrees on insulin resistance and islet β cell dysfunction and different epidemiological features. 15. 5% of Chinese ordinary adults developed ICR. IGR is significantly related with atherosclerotic cardiovascular diseases that independent of components of metabolic syndrome. Lifestyle intervention and relevant pharmacotherapy earlier are effective in reducing the incidence of diabetes and cardiovascular diseases in subjects with pre-diabetes.
