时珍国医国药
時珍國醫國藥
시진국의국약
LISHIZHEN MEDICINE AND MATERIA MEDICA RESEARCH
2009年
7期
1595-1596
,共2页
周雪娥%刘敏亮%谢小梅
週雪娥%劉敏亮%謝小梅
주설아%류민량%사소매
双向性固体发酵%灵雷菌质%耳肿胀%痛阈
雙嚮性固體髮酵%靈雷菌質%耳腫脹%痛閾
쌍향성고체발효%령뢰균질%이종창%통역
Bi-directional solid-state fungal fermentation%Ling lei fungal substance%Ear swelling%Pain threshold
目的 考察灵雷菌质的抗炎镇痛作用.方法 通过二甲苯致耳肿胀及醋酸引起毛细血管扩张法观察灵雷菌质的抗炎作用;采用热板法观察灵雷菌质的镇痛作用.结果 灵雷菌质对二甲苯所致小鼠耳肿胀和醋酸引起的毛细血管扩张有良好的抑制作用;并能提高热致痛小鼠的痛阈.结论 双向固体发酵后的灵雷菌质仍保留一定的抗炎与镇痛作用.
目的 攷察靈雷菌質的抗炎鎮痛作用.方法 通過二甲苯緻耳腫脹及醋痠引起毛細血管擴張法觀察靈雷菌質的抗炎作用;採用熱闆法觀察靈雷菌質的鎮痛作用.結果 靈雷菌質對二甲苯所緻小鼠耳腫脹和醋痠引起的毛細血管擴張有良好的抑製作用;併能提高熱緻痛小鼠的痛閾.結論 雙嚮固體髮酵後的靈雷菌質仍保留一定的抗炎與鎮痛作用.
목적 고찰령뢰균질적항염진통작용.방법 통과이갑분치이종창급작산인기모세혈관확장법관찰령뢰균질적항염작용;채용열판법관찰령뢰균질적진통작용.결과 령뢰균질대이갑분소치소서이종창화작산인기적모세혈관확장유량호적억제작용;병능제고열치통소서적통역.결론 쌍향고체발효후적령뢰균질잉보류일정적항염여진통작용.
Objective To research the anti-inflammatory and analgesic effects of fungal fermentative products in Tripterygium wilfordii Hook(ling lei fungal substance).Methods The models of ear swelling induced by dimethylbenzene and capillary permeability induced by acetic acid were used to observe the anti-inflammatory effect.Hot-plate method was used to observe the analgesic effect.Results The Fungal Fermentative Products in ling lei fungal substance could significantly reduce the capillary permeability of mice,inhibit ear swelling induced by dimethylbenzene in mice,and elevate pain threshold.Conclusion The fungal fermentation substances on ling lei fungal substance has anti-inflammatory and analgesic effects.
