国际生物医学工程杂志
國際生物醫學工程雜誌
국제생물의학공정잡지
INTERNATIONAL JOURNAL OF BIOMEDICAL ENGINEERING
2011年
5期
275-278,283
,共5页
杨光瑜%周继红%张岫竹%尹志勇%张良%宁心%董蕻%王伍超%王旭辉%刘大维
楊光瑜%週繼紅%張岫竹%尹誌勇%張良%寧心%董蕻%王伍超%王旭輝%劉大維
양광유%주계홍%장수죽%윤지용%장량%저심%동홍%왕오초%왕욱휘%류대유
共振频率%内脏%振动%大鼠%家兔
共振頻率%內髒%振動%大鼠%傢兔
공진빈솔%내장%진동%대서%가토
Resonance frequency%Bowels%Vibration%Rat%Rabbit
目的 研究低频振动条件下大鼠和家兔肠、肺、肾、胃、心、肝的共振频率和振动特点,为生物体器官共振损伤及其反应研究奠定基础.方法 SD大鼠和家兔各8只,1.5%戊巴比妥钠麻醉后,将加速度传感器固定于脏器表面.大鼠以仰卧位固定在用橡皮绳水平悬挂的胶合板上,从下往上锤击板底部,测量分析频谱响应,其最大值对应的频率即为共振频率;家兔以仰卧位固定在振动台上,施加振幅为2 mm的振动,振动频率范围为2~50 Hz,测量每个振动频率点的振幅,其最大振幅对应的频率即为共振频率.结果 在0~20 Hz频率范围内,大鼠肠、肺、肾、胃、心、肝在前后(胸背)方向的共振频率分别为3.8、3.2、6.6、7.0、4.6、3.0 Hz,在2~50 Hz频率范围内家兔肠、肺、肾、胃、心、肝在前后(胸背)方向的共振频率分别为6.0、5.0、7.0、8.0、6.0、7.0 Hz.在共振频率处肺的幅值最大;大鼠和家兔内脏的共振频率与体质量、脏器质量、脏器体积无明显统计相关性.结论 大鼠和家兔之间,除了肾以外,其它脏器共振频率其差异均有统计学意义;家兔内脏的共振频率在数值上比大鼠更接近于家狗和猴,可用家兔内脏的共振损伤特性作为家狗、猴甚至人体内脏共振损伤研究的基础.
目的 研究低頻振動條件下大鼠和傢兔腸、肺、腎、胃、心、肝的共振頻率和振動特點,為生物體器官共振損傷及其反應研究奠定基礎.方法 SD大鼠和傢兔各8隻,1.5%戊巴比妥鈉痳醉後,將加速度傳感器固定于髒器錶麵.大鼠以仰臥位固定在用橡皮繩水平懸掛的膠閤闆上,從下往上錘擊闆底部,測量分析頻譜響應,其最大值對應的頻率即為共振頻率;傢兔以仰臥位固定在振動檯上,施加振幅為2 mm的振動,振動頻率範圍為2~50 Hz,測量每箇振動頻率點的振幅,其最大振幅對應的頻率即為共振頻率.結果 在0~20 Hz頻率範圍內,大鼠腸、肺、腎、胃、心、肝在前後(胸揹)方嚮的共振頻率分彆為3.8、3.2、6.6、7.0、4.6、3.0 Hz,在2~50 Hz頻率範圍內傢兔腸、肺、腎、胃、心、肝在前後(胸揹)方嚮的共振頻率分彆為6.0、5.0、7.0、8.0、6.0、7.0 Hz.在共振頻率處肺的幅值最大;大鼠和傢兔內髒的共振頻率與體質量、髒器質量、髒器體積無明顯統計相關性.結論 大鼠和傢兔之間,除瞭腎以外,其它髒器共振頻率其差異均有統計學意義;傢兔內髒的共振頻率在數值上比大鼠更接近于傢狗和猴,可用傢兔內髒的共振損傷特性作為傢狗、猴甚至人體內髒共振損傷研究的基礎.
목적 연구저빈진동조건하대서화가토장、폐、신、위、심、간적공진빈솔화진동특점,위생물체기관공진손상급기반응연구전정기출.방법 SD대서화가토각8지,1.5%무파비타납마취후,장가속도전감기고정우장기표면.대서이앙와위고정재용상피승수평현괘적효합판상,종하왕상추격판저부,측량분석빈보향응,기최대치대응적빈솔즉위공진빈솔;가토이앙와위고정재진동태상,시가진폭위2 mm적진동,진동빈솔범위위2~50 Hz,측량매개진동빈솔점적진폭,기최대진폭대응적빈솔즉위공진빈솔.결과 재0~20 Hz빈솔범위내,대서장、폐、신、위、심、간재전후(흉배)방향적공진빈솔분별위3.8、3.2、6.6、7.0、4.6、3.0 Hz,재2~50 Hz빈솔범위내가토장、폐、신、위、심、간재전후(흉배)방향적공진빈솔분별위6.0、5.0、7.0、8.0、6.0、7.0 Hz.재공진빈솔처폐적폭치최대;대서화가토내장적공진빈솔여체질량、장기질량、장기체적무명현통계상관성.결론 대서화가토지간,제료신이외,기타장기공진빈솔기차이균유통계학의의;가토내장적공진빈솔재수치상비대서경접근우가구화후,가용가토내장적공진손상특성작위가구、후심지인체내장공진손상연구적기출.
Objective To find out the accurate resonance frequencies and vibration characteristics of intestine,lung,kidney,stomach,heart and liver of rat and rabbit in low frequency and to provide basic data for the study of organs' resonance injury and reaction.Methods Eight rats and eight rabbits were anaesthetized with 1.5% sodium pentobarbital and acceleration sensor was fixed to the surface of their bowels.The rats were fastened on their back on the veneer hung horizontally by rubber band.The veneer was hammered upward from the down side,and the biggest value of frequency spectrum was considered the resonance frequency.Rabbits were fastened on their back on vibration platform and 2 mm amplitude vibration was given with the sweeping-frequency from 2 Hz to 50 Hz.The bowels amplitudes on each frequency point were measured.The frequency corresponding to the biggest amplitude was considered the resonance frequency.Results The resonance frequencies of rat intestine,lung,kidney,stomach,heart and liver were respectively 3.8,3.2,6.6,7.0,4,6 and 3.0 Hz within frequency interval of 0 Hz to 20 Hz.The resonance frequencies of rabbit intestine,lung,kidney,stomach,heart and liver were respectively 6.0,5.0,7.0,8.0,6.0 and 7.0 Hz within frequency interval of 2 Hz to 50 Hz.The vibration amplitude of lung was the biggest at the resonance frequency.The resonance frequencies of both rat and rabbit bowels showed no statistical correlations to body weights,bowel mass and bowel volumes.Conclusion Bowel resonance frequencies of rat and that of rabbit are evidently statistical different except for that of kidney.The resonance frequency values of rabbit bowels are closer to that of dog and monkey than to that of rat.Thus the resonance injury characteristic of rabbit bowels can be the research basis for dog,monkey,and even human bowels resonance injury.