国际泌尿系统杂志
國際泌尿繫統雜誌
국제비뇨계통잡지
INTERNATIONAL JOURNAL OF UROLOGY AND NEPHROLOGY
2011年
4期
465-467
,共3页
黄永斌%张海涛%聂锐志%刘兆飞%刘希珍%林则馨
黃永斌%張海濤%聶銳誌%劉兆飛%劉希珍%林則馨
황영빈%장해도%섭예지%류조비%류희진%림칙형
前列腺肿瘤%膀胱颈梗阻%前列腺切除术
前列腺腫瘤%膀胱頸梗阻%前列腺切除術
전렬선종류%방광경경조%전렬선절제술
Prostatic Neoplasms%Bladder Neck Obstruction%Prostatectomy
目的 探讨经尿道等离子体前列腺切除联合抗雄治疗合并膀胱颈梗阻晚期高危前列腺癌的临床意义.方法 采用经尿道前列腺等离子切除术、去势术以及间歇雄激素阻断等综合方法治疗合并膀胱出口梗阻的晚期高危前列腺癌患者14例.结果 所有手术均成功施行.术前及术后3个月复查尿动力学指标,患者最大尿流率由(8.0±3.2)ml/s上升为(18.5±2.6)ml/s(p<0.05),国际前列腺症状评分由术前的(29.0±3.1)降为(8.0±1.5)(p<0.05),血清前列腺特异抗原由治疗前(51.3±19.4)ng/ml降至(8.8±6.1)ng/ml(p<0.01),生活质量评分由治疗前(4.4±1.3)降至(2.3±0.5)(p<0.05).随访6个月至今,其中2例分别于术后14个月～18个月死于前列腺癌,1例术后22个月死于其他疾病,其余患者带瘤存活.结论 合并膀胱出口梗阻的前列腺癌采用经尿道前列腺等离子切除术、去势术和间歇雄激素阻断的综合治疗具有创伤小、恢复快等优点,且能提高患者的生存质量并延长患者生存期.
目的 探討經尿道等離子體前列腺切除聯閤抗雄治療閤併膀胱頸梗阻晚期高危前列腺癌的臨床意義.方法 採用經尿道前列腺等離子切除術、去勢術以及間歇雄激素阻斷等綜閤方法治療閤併膀胱齣口梗阻的晚期高危前列腺癌患者14例.結果 所有手術均成功施行.術前及術後3箇月複查尿動力學指標,患者最大尿流率由(8.0±3.2)ml/s上升為(18.5±2.6)ml/s(p<0.05),國際前列腺癥狀評分由術前的(29.0±3.1)降為(8.0±1.5)(p<0.05),血清前列腺特異抗原由治療前(51.3±19.4)ng/ml降至(8.8±6.1)ng/ml(p<0.01),生活質量評分由治療前(4.4±1.3)降至(2.3±0.5)(p<0.05).隨訪6箇月至今,其中2例分彆于術後14箇月～18箇月死于前列腺癌,1例術後22箇月死于其他疾病,其餘患者帶瘤存活.結論 閤併膀胱齣口梗阻的前列腺癌採用經尿道前列腺等離子切除術、去勢術和間歇雄激素阻斷的綜閤治療具有創傷小、恢複快等優點,且能提高患者的生存質量併延長患者生存期.
목적 탐토경뇨도등리자체전렬선절제연합항웅치료합병방광경경조만기고위전렬선암적림상의의.방법 채용경뇨도전렬선등리자절제술、거세술이급간헐웅격소조단등종합방법치료합병방광출구경조적만기고위전렬선암환자14례.결과 소유수술균성공시행.술전급술후3개월복사뇨동역학지표,환자최대뇨류솔유(8.0±3.2)ml/s상승위(18.5±2.6)ml/s(p<0.05),국제전렬선증상평분유술전적(29.0±3.1)강위(8.0±1.5)(p<0.05),혈청전렬선특이항원유치료전(51.3±19.4)ng/ml강지(8.8±6.1)ng/ml(p<0.01),생활질량평분유치료전(4.4±1.3)강지(2.3±0.5)(p<0.05).수방6개월지금,기중2례분별우술후14개월～18개월사우전렬선암,1례술후22개월사우기타질병,기여환자대류존활.결론 합병방광출구경조적전렬선암채용경뇨도전렬선등리자절제술、거세술화간헐웅격소조단적종합치료구유창상소、회복쾌등우점,차능제고환자적생존질량병연장환자생존기.
Objectives Discussion PKRP joint androgen deprivation therapy high-risk merger bladder neck obstruction of the highly dangerous adanced prostate cancer clinical significance.Methods 14 cases of prostatic carcinoma complicated with bladder outlet obstruction were treated with bilateral orehidectomy combined with transurethral resection of the prostate plasma(PKRP)and intermittent nude hormone blockage.Results All the operations succeeded.Preoperative and postoperative 3 months review urine dynamics index,Qmax increased from (8.0±3.2)ml/s to(18.5±2.6)ml/s(p<0.05),IPSS decreased from(29.0±3.1)preoperatively to(8.0±1.5)postoperatively(p<0.05),QOL decreased from(4.4±1.3)to(2.3±0.5)(p0.05),,PSA decreased from (51.3±19.4)ng/ml to(8.8±6.1)ng/ml(P0.01).The follow up was 6months to today.2 cases died of prostatic carcinoma and 1 cases died of other diseases.The others survived with carcinoma.Conclusions Combined therapy,which includes bilateral orchidectomy,PKRP and intermittent male hormone blockage,for prostatic carcino ma complicated with bladder outlet obstruction has advantages of minimal trauma and rapid recovery.It can prolong life span,improve the quality of life,and be worth of wide application.
