CAJ | 학술논문

目的探讨治疗中央区癫痫的手术方法及提示手术预后的相关因素.方法以自2006年10月至2008年3月北京功能神经外科研究所连续收治的21例中央区癫痫患者为研究对象,行致痫灶切除术.术后随访12个月以上,Engel分级Ⅰ、Ⅱ级为预后良好,分析与预后良好相关的因素.结果 Engel分级Ⅰ、Ⅱ级共14例(67％).MRI可见病变与MRI无病变相比,预后良好率较高(P＜0.05)；病理为局灶性皮质发育不良患者与其他病理患者相比,预后良好率较低(P＜0.05).结论中央区癫痫经精确定位功能区及致痫灶,行致痫灶切除,总体预后良好.MRI可见病变提示预后良好,病理为局灶性皮质发育不良较其他病理改变预后差.
목적 탐토치료중앙구전간적수술방법급제시수술예후적상관인소.방법 이자2006년10월지2008년3월북경공능신경외과연구소련속수치적21례중앙구전간환자위연구대상,행치간조절제술.술후수방12개월이상,Engel분급Ⅰ、Ⅱ급위예후량호,분석여예후량호상관적인소.결과 Engel분급Ⅰ、Ⅱ급공14례(67％).MRI가견병변여MRI무병변상비,예후량호솔교고(P＜0.05)；병리위국조성피질발육불량환자여기타병리환자상비,예후량호솔교저(P＜0.05).결론 중앙구전간경정학정위공능구급치간조,행치간조절제,총체예후량호.MRI가견병변제시예후량호,병리위국조성피질발육불량교기타병리개변예후차.
Objective The purpose of the study was to investigate effective surgical procedure for perirolandic epilepsy and the predictor for good outcomes.Method We collected 21 subjects who underwent epilepsy surgeries consecutively in Beijing Institute of Functional Neurosurgery with the epileptogenic zone located in perirolandic areas from October 2006 to March 2008.Over 12 -month following up and Engel Ⅰ and Ⅱ taken as “good” outcomes,we analyzed the predicting factors for good outcomes.Results At the end of follow up,Engel class Ⅰ and Ⅱ were 14 cases(67％ ).Patients with lesion in MRI obtained better outcomes and patients with focal cortex dysplasia(FCD) pathology obtained worse outcomes regarding the rate of Engel class Ⅰ + Ⅱ( P ＜ 0.05).There were no serious functional deficits.Conclusions Surgical resection of epileptogenic zone for periroladic epilepsy can achieve good outcomes.Patients with lesion in MRI predicted better outcomes and FCD pathology predicted worse outcome.