医药导报
醫藥導報
의약도보
HERALD OF MEDICINE
2001年
2期
95-96
,共2页
李德香%闫士广%李学松%李仁祧%李茂绪%车峰远
李德香%閆士廣%李學鬆%李仁祧%李茂緒%車峰遠
리덕향%염사엄%리학송%리인조%리무서%차봉원
硫酸镁%癫癎,顽固性%卡马西平
硫痠鎂%癲癎,頑固性%卡馬西平
류산미%전간,완고성%잡마서평
目的：探讨硫酸镁辅助治疗顽固性癫癎的剂量、方法及疗效。方法：治疗组72例，用25%硫酸镁10 mL静脉滴注，或用16.5%硫酸镁10 mL口服。对照组36例给予常规抗癫癎药物，卡马西平或苯妥英钠加苯巴比妥或氯硝西泮加用γ-氨基丁酸等治疗。结果：治疗组有效率87.5%，对照组有效率44.4%，两组比较经统计学分析P＜0.01，差异极显著。结论：硫酸镁联合一线抗癫癎药治疗顽固性癫癎的方法简单易行，具有良好效果。
目的：探討硫痠鎂輔助治療頑固性癲癎的劑量、方法及療效。方法：治療組72例，用25%硫痠鎂10 mL靜脈滴註，或用16.5%硫痠鎂10 mL口服。對照組36例給予常規抗癲癎藥物，卡馬西平或苯妥英鈉加苯巴比妥或氯硝西泮加用γ-氨基丁痠等治療。結果：治療組有效率87.5%，對照組有效率44.4%，兩組比較經統計學分析P＜0.01，差異極顯著。結論：硫痠鎂聯閤一線抗癲癎藥治療頑固性癲癎的方法簡單易行，具有良好效果。
목적：탐토류산미보조치료완고성전간적제량、방법급료효。방법：치료조72례，용25%류산미10 mL정맥적주，혹용16.5%류산미10 mL구복。대조조36례급여상규항전간약물，잡마서평혹분타영납가분파비타혹록초서반가용γ-안기정산등치료。결과：치료조유효솔87.5%，대조조유효솔44.4%，량조비교경통계학분석P＜0.01，차이겁현저。결론：류산미연합일선항전간약치료완고성전간적방법간단역행，구유량호효과。
Objective:To determine the dosage,method and effectiveness of using magnesium sulfate for treating the intractable epilepsy.Methods:72 cases were allocated to treatment group and 36 to control group. For those in the treatment group,either 10 mL of 25% MgSO4 was administered by intravenous drip or 10 mL of 16.5% MgSO4 by oral intake once per day,in addition to the use of the commonly used antiepilepsy drugs. For those in the control group,the commonly used antiepilepsy drugs such as tegretol,sodium phenytoin,luminal or γ-Aminobutyric Acid were employed.Results:The improvement rate in the treatment group was 87.50%,higher than that (44.44%) in the control group (P＜0.01).Conclusion:Using magnesium sulfate in conjunction with the antiepilepsy drugs is a simple yet effective regime for the treatment of the intractable epilepsy.
