中国综合临床
中國綜閤臨床
중국종합림상
CLINICAL MEDICINE OF CHINA
2011年
9期
997-999
,共3页
磷酸肌酸%婴儿%肺炎%心肌损害
燐痠肌痠%嬰兒%肺炎%心肌損害
린산기산%영인%폐염%심기손해
Phosphocreatine%Infant%Pneumonia%Myocardial injury
目的 探讨磷酸肌酸治疗婴儿肺炎合并心肌损害的临床疗效。方法 68例婴儿肺炎合并心肌损害的患儿随机分为治疗组(36例)和对照组(32例),2组均给予抗感染、祛痰、平喘、能量支持综合治疗;治疗组在此基础上加用磷酸肌酸。对2组患儿心电图、心肌酶谱恢复情况、主要症状与体征恢复时间及住院时间进行比较分析。结果 治疗组患儿心肌酶谱、心电图恢复正常率(均为94.44％)与对照组(分别为78.13％和75.00％)比较差异有统计学意义(x2值分别为3.93和5.11,P均＜0.05);主要症状[咳嗽恢复时间(9.5±2.4)d与(11.1±2.6)d]与体征恢复时间[啰音吸收时间(8.1±1.9) d与(10.3±2.4)d]均明显短于对照组(t值分别为2.63和4.16,P＜0.05和P＜0.01),住院时间[(11.5±2.2)d与(14.3±2.8)d]明显缩短,差异有统计学意义(t=4.55,P＜0.01)。结论 磷酸肌酸治疗婴儿肺炎合并心肌损害疗效显著,安全有效。
目的 探討燐痠肌痠治療嬰兒肺炎閤併心肌損害的臨床療效。方法 68例嬰兒肺炎閤併心肌損害的患兒隨機分為治療組(36例)和對照組(32例),2組均給予抗感染、祛痰、平喘、能量支持綜閤治療;治療組在此基礎上加用燐痠肌痠。對2組患兒心電圖、心肌酶譜恢複情況、主要癥狀與體徵恢複時間及住院時間進行比較分析。結果 治療組患兒心肌酶譜、心電圖恢複正常率(均為94.44％)與對照組(分彆為78.13％和75.00％)比較差異有統計學意義(x2值分彆為3.93和5.11,P均＜0.05);主要癥狀[咳嗽恢複時間(9.5±2.4)d與(11.1±2.6)d]與體徵恢複時間[啰音吸收時間(8.1±1.9) d與(10.3±2.4)d]均明顯短于對照組(t值分彆為2.63和4.16,P＜0.05和P＜0.01),住院時間[(11.5±2.2)d與(14.3±2.8)d]明顯縮短,差異有統計學意義(t=4.55,P＜0.01)。結論 燐痠肌痠治療嬰兒肺炎閤併心肌損害療效顯著,安全有效。
목적 탐토린산기산치료영인폐염합병심기손해적림상료효。방법 68례영인폐염합병심기손해적환인수궤분위치료조(36례)화대조조(32례),2조균급여항감염、거담、평천、능량지지종합치료;치료조재차기출상가용린산기산。대2조환인심전도、심기매보회복정황、주요증상여체정회복시간급주원시간진행비교분석。결과 치료조환인심기매보、심전도회복정상솔(균위94.44％)여대조조(분별위78.13％화75.00％)비교차이유통계학의의(x2치분별위3.93화5.11,P균＜0.05);주요증상[해수회복시간(9.5±2.4)d여(11.1±2.6)d]여체정회복시간[라음흡수시간(8.1±1.9) d여(10.3±2.4)d]균명현단우대조조(t치분별위2.63화4.16,P＜0.05화P＜0.01),주원시간[(11.5±2.2)d여(14.3±2.8)d]명현축단,차이유통계학의의(t=4.55,P＜0.01)。결론 린산기산치료영인폐염합병심기손해료효현저,안전유효。
Objective To evaluate the effect of phosphocreatine in the treatment of infant with Pneumonia complicated with myocardial injury.Methods Sixty-eight infants with Pneumonia complicated with myocardial injury were randomized into treatment group (n = 36) and control group (n = 32) .The two groups were both treated with combined anti-infection, antiasthmatic and supporting treatments while the treatment group was given additional phosphocreatine.The ECG,recovery of myocardial enzymes, recovery time of major clinical symptoms and syndromes and the period of hospitalization of the two groups were compared.Results Recovery of ECG and myocardial enzymes in the treatment group (94.44％ and 94.44％) were significantly higher than those in the control group(78.13％ and 75.00％ ,respectively) (x2 =3.93 and 5.11 ,respectively,P ＜0.05).Recovery of clinical presentations were more rapid in the treatment group than that in control group (time for cough recovery, [9.5 ± 2.4]d vs.[11.1 ± 2.6]d ;time for rale disappearance, [8.1 ± 1.9]d vs.[10.3 ± 2.4]d) (t =2.63 and t =4.16 respectively ;P ＜0.05 and ＜0.01 respectively).The period of hospitalization was decreased markedly in the treatment group compared with that in the control group([11.5 ±2.2]d vs.[14.3 ±2.8]d) (t = 4.55, P ＜ 0.01) .Conclusion Phosphocreatine has prominent efficacy in the treatment of infantile Pneumonia complicated with myocardial injury.
