CAJ | 학술논문

目的探讨老年胃癌患者行手术治疗后的治疗效果、临床特点及年龄与预后的关系.方法对年龄≥70岁、有完整临床资料及随访结果的112例胃癌患者进行回顾性分析,并随机抽取同期年龄＜50岁的135例患者作对照.结果老年组患者术前并发症多,肿瘤多为高分化及中分化(P＜0.05),而对照组中低分化,印戒细胞癌所占比例较高,肿瘤分型中,对照组多为Borrmann Ⅳ型(P＜0.05)；而两组患者术前肝功能、肿瘤浸润程度、淋巴结转移数目、肝脏转移及腹膜转移情况、肿瘤pTNM分期及手术方式、术后并发症发生率、术后5年生存率等方面差异均无统计学意义(均P＞0.05).结论对于没有合并术前并发症或能够有效控制术前并发症的老年胃癌患者而言,手术治疗是安全的,可作为治疗的首选方案.
목적 탐토노년위암환자행수술치료후적치료효과、림상특점급년령여예후적관계.방법 대년령≥70세、유완정림상자료급수방결과적112례위암환자진행회고성분석,병수궤추취동기년령＜50세적135례환자작대조.결과 노년조환자술전병발증다,종류다위고분화급중분화(P＜0.05),이대조조중저분화,인계세포암소점비례교고,종류분형중,대조조다위Borrmann Ⅳ형(P＜0.05)；이량조환자술전간공능、종류침윤정도、림파결전이수목、간장전이급복막전이정황、종류pTNM분기급수술방식、술후병발증발생솔、술후5년생존솔등방면차이균무통계학의의(균P＞0.05).결론 대우몰유합병술전병발증혹능구유효공제술전병발증적노년위암환자이언,수술치료시안전적,가작위치료적수선방안.
Objective To explore the operation effect and clinicopathologic characteristics of elderly patients with gastric carcinoma(GC) and the relationship between prognosis and age.Methods The clinical data and treatment outcomes of 112 elderly patients suffered from GC( elderly group≥70 years of age) and 135 younger patients (control group ＜50 years of age) were analyzed retrospectively.Results The elderly GC patients had more preoperative comorbidities,and a well or moderately differentiated histology(P ＜0.05).And more young patients had a poorly differentiated histology and signet ring cell carcinoma,using the Borrmann classification,type Ⅳ was more frequent in the young patients(P ＜0.05 ) ; Whereas there were no significant differences beween the two groups in other factors ( including liver function,tumor invasion,nodal involvement,hepatic metastasis,peritoneal dissemination,tumor stage,type of surgery,post operation complication and 5-year survival rates of elderly patients and young patients) ( all P ＜0.05).Conclusion Outcomes in elderly patients with gastric carcinoma were comparable to young patients.The important prognostic factor was whether the patients undergo a curative resection.For the elderly patients without preoperative comorbidities or with controlled comorbidities,gastrectomy was a safe and effective treatment.