CAJ | 학술논문

目的观察敷脐巴布剂对胃手术模型大鼠胃肠运动和胃肠激素的影响,探讨其可能的作用机制.方法 ①观察胃手术模型大鼠用敷脐巴布剂敷脐后碳素墨水在小肠的移动长度,并与巴布剂基质组、手术模型组进行比较;②用放射免疫分析法测定巴布剂敷脐10 d后大鼠小肠组织胃动素(MOT)和生长抑素(SS)的水平.结果 ①敷脐巴布剂组能明显提高碳素墨水在大鼠小肠的推进距离与百分比,与巴布剂基质组及手术模型组比较差异显著(P＜0.01),巴布剂基质组与手术模型组无显著差异(P＞0.05);②敷脐巴布剂可提高大鼠小肠组织MOT及降低小肠组织SS水平,与手术模型组比较差异显著(P＜0.05或P＜0.01).结论敷脐巴布剂能促进胃手术模型大鼠术后胃肠蠕动,对胃肠激素水平有调节作用.
목적 관찰부제파포제대위수술모형대서위장운동화위장격소적영향,탐토기가능적작용궤제.방법 ①관찰위수술모형대서용부제파포제부제후탄소묵수재소장적이동장도,병여파포제기질조、수술모형조진행비교;②용방사면역분석법측정파포제부제10 d후대서소장조직위동소(MOT)화생장억소(SS)적수평.결과 ①부제파포제조능명현제고탄소묵수재대서소장적추진거리여백분비,여파포제기질조급수술모형조비교차이현저(P＜0.01),파포제기질조여수술모형조무현저차이(P＞0.05);②부제파포제가제고대서소장조직MOT급강저소장조직SS수평,여수술모형조비교차이현저(P＜0.05혹P＜0.01).결론 부제파포제능촉진위수술모형대서술후위장연동,대위장격소수평유조절작용.
Purpose To observe the effects of umbilical cataplasm on rat gastrointestinal motility and gastrointestinal hormones using rat model of gastric operation,and to explore its possible mechanism.Methods ①The peristalsis length of carbon ink in small intestine of 20 rats was investigated by the use of umbilical cataplasm,compared with the matrix cataplasm group and the untreated control group. ②By means of radioimmunoassay,the levels of motilin(MOT) and somatostatin(SS) in small intestine tissue of 20 rats were investigated after a ten-day course of application of umbilical cataplasm.Results ①The group of umbilical cataplasm could significantly increase the peristalsis length of carbon ink in the rat small intestine and the distance percentage to the whole intestine,compared with the matrix cataplasm group and the untreated control group has significant difference(P＜0.01),and has no significant differernce between the other two groups(P＞0.05). ②Umbilical cataplasm can increase the levels of MOT and decrease the levels of SS in small intestine tissue of rat,compared with the untreated group P＜0.05 or P<0.01.Conclusion Umbilical cataplasm can promote gastrointestinal peristalsis of the rat model of gastric operation, and can regulate the levels of gastrointestinal hormones.