中国介入影像与治疗学
中國介入影像與治療學
중국개입영상여치료학
CHINESE JOURNAL OF INTERVENTIONAL IMAGING AND THERAPY
2010年
1期
43-46
,共4页
体层摄影术%X线计算机%灌注成像%减影技术%卒中%脑肿瘤
體層攝影術%X線計算機%灌註成像%減影技術%卒中%腦腫瘤
체층섭영술%X선계산궤%관주성상%감영기술%졸중%뇌종류
Tomography%X-ray computed%Perfusion imaging%Subtraction technique%Stroke%Brain neoplasms
目的 探讨脑减影CT灌注成像(sCTP)技术及其初步应用.方法 选取11例有脑CTP源影像的患者,其中脑梗死10例、脑瘤1例,在AW 4.2工作站利用减影软件先行减影处理,再以Perfusion 3软件对减影图像数据和源影像数据分别作灌注成像分析,测量血流量(BF)、血容量(BV)、平均通过时间(MTT)、毛细血管通透性(PS)数值并生成其色阶图,进行组间、区间比较与分析.结果 ①脑sCTP技术成功率为100%,均获得了有诊断价值的BF、BV、MTT或PS色阶图及其数值,其后处理时间约需1～2.5 h;②sCTP提供的BF、BV、MTT、PS色阶图与CTP的类似,均准确揭示了病变及微循环血液动力学情况;③与CTP类似,脑sCTP提供的BF、BV、MTT、PS数值病变与毗邻及对侧组织有显著性差异(P<0.025).结论 脑sCTP技术可行,是减影技术结合灌注成像技术的产物,可作为脑卒中、脑肿瘤功能成像诊断的补充和可选择的检查手段.
目的 探討腦減影CT灌註成像(sCTP)技術及其初步應用.方法 選取11例有腦CTP源影像的患者,其中腦梗死10例、腦瘤1例,在AW 4.2工作站利用減影軟件先行減影處理,再以Perfusion 3軟件對減影圖像數據和源影像數據分彆作灌註成像分析,測量血流量(BF)、血容量(BV)、平均通過時間(MTT)、毛細血管通透性(PS)數值併生成其色階圖,進行組間、區間比較與分析.結果 ①腦sCTP技術成功率為100%,均穫得瞭有診斷價值的BF、BV、MTT或PS色階圖及其數值,其後處理時間約需1～2.5 h;②sCTP提供的BF、BV、MTT、PS色階圖與CTP的類似,均準確揭示瞭病變及微循環血液動力學情況;③與CTP類似,腦sCTP提供的BF、BV、MTT、PS數值病變與毗鄰及對側組織有顯著性差異(P<0.025).結論 腦sCTP技術可行,是減影技術結閤灌註成像技術的產物,可作為腦卒中、腦腫瘤功能成像診斷的補充和可選擇的檢查手段.
목적 탐토뇌감영CT관주성상(sCTP)기술급기초보응용.방법 선취11례유뇌CTP원영상적환자,기중뇌경사10례、뇌류1례,재AW 4.2공작참이용감영연건선행감영처리,재이Perfusion 3연건대감영도상수거화원영상수거분별작관주성상분석,측량혈류량(BF)、혈용량(BV)、평균통과시간(MTT)、모세혈관통투성(PS)수치병생성기색계도,진행조간、구간비교여분석.결과 ①뇌sCTP기술성공솔위100%,균획득료유진단개치적BF、BV、MTT혹PS색계도급기수치,기후처리시간약수1～2.5 h;②sCTP제공적BF、BV、MTT、PS색계도여CTP적유사,균준학게시료병변급미순배혈액동역학정황;③여CTP유사,뇌sCTP제공적BF、BV、MTT、PS수치병변여비린급대측조직유현저성차이(P<0.025).결론 뇌sCTP기술가행,시감영기술결합관주성상기술적산물,가작위뇌졸중、뇌종류공능성상진단적보충화가선택적검사수단.
Objective To investigate the possibility to obtain the cranial subtraction computed tomography perfusion imaging (sCTP) from the CTP examination, and to explore preliminary application value of sCTP. Methods Cerebral sCTP obtained from source imaging data of 11 patients (10 with stroke and 1 with brain tumor) were analyzed with subtraction software and perfusion 3 software at GE AW4.2 workstation. The parametric maps and region of interest (ROI) value of blood flow (BF), blood volume (BV), mean transit time (MTT) and/or permeability surface (PS) were generated from the CTP and sCTP imaging data respectively. Results ①The technical success rate of cranial sCTP created from CTP sources imaging data was 100%, and the post-processing time of sCTP was about from 1.0 to 2.5 h. The mappings and values of BF, BV, MTT and PS of ROI were all successfully obtained from sCTP and CTP imaging data. ②The cerebral mappings of BF, BV, MTT and PS obtained from sCTP were similar to those from CTP, which all depicted accurately the lesions and their microcirculation hemodynamics changes. ③Just like those from CTP, the values of BF, BV, MTT and PS of nidus obtained from sCTP were significantly different from those of the near and the contralateral corresponding cerebral tissues (P<0.025). Conclusion sCTP can be generated successfully with subtraction and perfusion imaging software. It is an alternative solution for functional diagnosis of stroke and brain neoplasms.
