CAJ | 학술논문

目的探讨儿童与成人在急性氯气中毒后临床特点的区别.方法对急性氯气中毒患者24 h内的临床表现、实验室结果及中毒第8天后肺功能检查结果进行回顾性分析.结果儿童与成人急性氯气中毒患者相比,重度中毒患儿的比例高于成人;中毒后24 h内胃肠道反应、意识障碍、窦性心动过速、一过性的血压升高、急性呼吸窘迫综合征(ARDS)、呼吸性酸中毒、血白细胞和中性粒细胞升高的发生率等方面,儿童明显高于成人(P<0.05);儿童与成人患者呼吸道刺激症状、呼吸困难和血乳酸增多的发生率相比差异无统计学意义(P>0.05);中毒第8天,FVC、FEV_1(>80%预计值)儿童与成人相比差异无统计学意义(P>0.05).结论儿童急性氯气中毒后临床症状较重,能迅速发展为ARDS;经过及时有效的治疗后,儿童肺功能的恢复早于成人.
목적 탐토인동여성인재급성록기중독후림상특점적구별.방법 대급성록기중독환자24 h내적림상표현、실험실결과급중독제8천후폐공능검사결과진행회고성분석.결과 인동여성인급성록기중독환자상비,중도중독환인적비례고우성인;중독후24 h내위장도반응、의식장애、두성심동과속、일과성적혈압승고、급성호흡군박종합정(ARDS)、호흡성산중독、혈백세포화중성립세포승고적발생솔등방면,인동명현고우성인(P<0.05);인동여성인환자호흡도자격증상、호흡곤난화혈유산증다적발생솔상비차이무통계학의의(P>0.05);중독제8천,FVC、FEV_1(>80%예계치)인동여성인상비차이무통계학의의(P>0.05).결론 인동급성록기중독후림상증상교중,능신속발전위ARDS;경과급시유효적치료후,인동폐공능적회복조우성인.
Objective To investigate the difference between children and adults in clinical characteristics after acute chlorine exposure. Methods We performed a retrospective study on clinical and laboratory indicators within 24 hours, and pulmonary function tests after 8 days. Results The proportion of severe poisoning in children was higher than those in adults. Within 24 hours, the incidences of gastrointestinal reaction, conscious disturbance, sinus tachycardia, a transient increase in blood pressure, acute respiratory distress syndrome (ARDS), respiratory acidosis, and the level of leukocyte and neutrophil in children patients were significantly higher than those in adult ones (P<0.05). There was no significant difference in respiratory irritation symptoms, dyspnea, the level of blood lactate within 24 hours, and in pulmonary function FVC and FEV_1 (>80% predicted) between child and adult patients after 8 days (P>0.05). Conclusion Children patients with acute chlorine gas inhalation appear more serious clinical symptoms, and develop into ARDS rapidly. After appropriate treatment, the pulmonary function of children patients recover earlier than adult ones.