CAJ | 학술논문

目的观察三维适形放疗对食管癌患者的疗效及其急性毒副反应。方法初治食管癌患者72例，全部接受三维适形放射治疗，治疗剂量为6000～7000 cGy，中位处方剂量为6400 cGy，200 cGy/次，1次/天,5次/周。评价三维适形放疗的效果及其可能的急性毒副作用。结果全组患者完全缓解(CR)45例；部分缓解(PR)26例；无缓解(NR)1例。肿瘤总有效率(CR+PR)为98.61％。急性放射性肺炎0级44例，1级19例，2级8例，3级1例，4级0例；急性放射性食管炎0级15例,1级38例，2级15例,3级4例，无4级发生。结论三维适形放疗可明显改善食管癌患者的治疗效果，但其远期疗效需进一步观察。
목적 관찰삼유괄형방료대식관암환자적료효급기급성독부반응。방법 초치식관암환자72례，전부접수삼유괄형방사치료，치료제량위6000～7000 cGy，중위처방제량위6400 cGy，200 cGy/차，1차/천,5차/주。평개삼유괄형방료적효과급기가능적급성독부작용。결과 전조환자완전완해(CR)45례；부분완해(PR)26례；무완해(NR)1례。종류총유효솔(CR+PR)위98.61％。급성방사성폐염0급44례，1급19례，2급8례，3급1례，4급0례；급성방사성식관염0급15례,1급38례，2급15례,3급4례，무4급발생。결론 삼유괄형방료가명현개선식관암환자적치료효과，단기원기료효수진일보관찰。
Objective To observe the curative effect and acute adverse reaction of three-dimensional conformal radiotherapy to esophageal cancer patients. Methods 72 cases of esophageal cancer, all accepted three-dimensional conformal radiotherapy, therapeutic doses of 6000 to 7000 cGy, median prescribed dose 6400 cGy, 200 cGy per time, 1 time per day, five times per week. We evaluated the effects of threedimensional conformal radiotherapy and its possible acute adverse reaction toxicity. Results Among all patients, 45 with complete remission (CR; 26 ones with part remission (PR); No remission (NR) in one. 98.61％for tumor total effectiveness (CR + PR). Acute radioactive pneumonia 0 level, 44 cases; 19 cases with level 1, 8cases for 2nd level, grade 3 in 1, 4 level, 0; acute radioactive esophagitis 15 in level 0, 38 in level 1, 15 in level 2, 4 in level 3, but none in level 4. Conclusion Three-dimensional conformal radiotherapy can obviously improve the therapeutic effect of esophageal cancer patients, but the long-term efficacy needs further observation.