CAJ | 학술논문

目的探讨利用吲哚青绿血管造影检查作为原田(Harada)病临床观察指标的意义.方法对经药物治疗后19例(38只眼)原田病患者同时行荧光素眼底血管造影(fundus fluorescein angiography,FFA)及吲哚青绿血管造影(indocyanine green angiography,ICGA)检查资料进行分析.结果 FFA检查发现有4例(8只眼)视盘轻度染色,视网膜未发现异常改变;ICGA早期及中期无异常表现,但后期8只眼(包括FFA中视盘染色的4只眼)在中周及后极部出现了点状或斑片状弱荧光;3例6只眼FFA及眼底正常,在ICGA后期后极部出现了斑点状弱荧光;24只眼脉络膜大、中血管影像减少,其中12只眼dalen-fuchs结节着色.结论 ICGA可较好提供原田病的脉络膜循环损害的信息,并在评价疗效上有意义.
목적 탐토이용신타청록혈관조영검사작위원전(Harada)병림상관찰지표적의의.방법 대경약물치료후19례(38지안)원전병환자동시행형광소안저혈관조영(fundus fluorescein angiography,FFA)급신타청록혈관조영(indocyanine green angiography,ICGA)검사자료진행분석.결과 FFA검사발현유4례(8지안)시반경도염색,시망막미발현이상개변;ICGA조기급중기무이상표현,단후기8지안(포괄FFA중시반염색적4지안)재중주급후겁부출현료점상혹반편상약형광;3례6지안FFA급안저정상,재ICGA후기후겁부출현료반점상약형광;24지안맥락막대、중혈관영상감소,기중12지안dalen-fuchs결절착색.결론 ICGA가교호제공원전병적맥락막순배손해적신식,병재평개료효상유의의.
Objective To investigate the clinical value of indocyanine green angiography(ICGA)in patients with Harada disease.Methods Fundus fluorescein angiography(FFA)and indocyanine green angiography(ICGA)were used for comparative analyses in 26 cases(52 eyes)of Harada disease after treatment.Results Mild dyeing in disk was found only in 4 cases(8 eyes),and the others were not found any abnormal in FFA.There were no any abnormal found in early period and middle period of ICGA,but of 8 eyes(include 4 eyes of dyeing in disk in FFA)multifocal lower fluorescence were found in the mid-periphery and posterior pole of the fundus in the late phase.Of 3 cases(6 eyes)were normal in FFA,however multifocal lower fluorescence were found in the posterior pole of the fundus in the late phase of ICGA.Of 24 eyes were found decreased fluorescence in large and middle choroidal vessel,and 12 eyes of Dalen-Fuchs were colored.Conclusions ICGA may assist in providing valuable information on choroidal circulation of Harada disease and be useful in evaluating the curative effects.