CAJ | 학술논문

目的:探讨~(99m)Tc-甲氧基异丁基异腈(MIBI)门控核素心肌灌注显像(G-MPI)在预测冠状动脉介入治疗(冠状动脉支架置入术)疗效方面的价值.方法:30例接受经皮冠状动脉支架置入术的冠心病患者均在支架置入术前1周及随访期内(5.67±3.23个月)完成两日法负荷/静息G-MPI,在支架置入术和随访核素心肌灌注显像之间无主要不良心脏事件的发生,比较术前及随访期的G-MPI定性和定量分析的结果.结果:G-MPI示支架置入术后缺血心肌节段数[(1.77±2.06)个]明显少于术前[(4.57±2.93)个](P=0.000),梗死心肌节段数则无显著差异(P=0.599).支架术后总负荷评分和负荷静息评分差值较术前明显降低(P值分别为0.001和0.002).支架置入术后,患者的LVEF由(56.43±16.59)%升高至(62.50±19.05)%(P=0.003),左室舒张末容积和左室收缩末容积均明显降低(P分别为0.005和0.000).结论:术前行核素心肌显像判断缺血存活心肌的情况,可以对支架置入术的疗效进行较为准确的预测,门控采集所获得的心室功能和容积也有助于对患者进行危险度分层.
목적:탐토~(99m)Tc-갑양기이정기이정(MIBI)문공핵소심기관주현상(G-MPI)재예측관상동맥개입치료(관상동맥지가치입술)료효방면적개치.방법:30례접수경피관상동맥지가치입술적관심병환자균재지가치입술전1주급수방기내(5.67±3.23개월)완성량일법부하/정식G-MPI,재지가치입술화수방핵소심기관주현상지간무주요불양심장사건적발생,비교술전급수방기적G-MPI정성화정량분석적결과.결과:G-MPI시지가치입술후결혈심기절단수[(1.77±2.06)개]명현소우술전[(4.57±2.93)개](P=0.000),경사심기절단수칙무현저차이(P=0.599).지가술후총부하평분화부하정식평분차치교술전명현강저(P치분별위0.001화0.002).지가치입술후,환자적LVEF유(56.43±16.59)%승고지(62.50±19.05)%(P=0.003),좌실서장말용적화좌실수축말용적균명현강저(P분별위0.005화0.000).결론:술전행핵소심기현상판단결혈존활심기적정황,가이대지가치입술적료효진행교위준학적예측,문공채집소획득적심실공능화용적야유조우대환자진행위험도분층.
Objective:To investigate the clinic value of using ~(99m)Tc-MIBI gated myocardium perfusion imaging (G-MPI) to predict effect of percutaneous coronary intervention (stent implantation). Method:Thirty patients of CAD with stent implantation underwent stress/rest ~(99m)Tc-MIBI G-MPI before (1 week) and after (5.67±3.23 months) PCI procedure respectively and the results of G-MPI were compared. The patients had not severe adverse event within the following period after PCI.Result:The amount of segments of ischemic myocardium after PCI (1.77±2.06) was less than those before PCI (4.57±2.93) significantly (P=0.000) and the segments of infarct myocardium were similar (P=0.599). The values of SSS and SDS after PCI were lower than those before PCI significantly (P=0.001 and 0.002 respectively). After stent implantation, the value of LVEF was higher (P=0.003),while the values of LVEDV and LVESV were lower rather than those before PCI (P=0.005 and 0.000 respectively).Conclusion:G-MPI had good clinic value to predict the effect of PCI.