CAJ | 학술논문

转化生长因子β(transforming growth factor-β,TGF-β)是启动和终止炎症和组织修复的调节因子,是参与调控肺纤维化发生的细胞因子.TGF-β亚单位功能与其种类以及与受体的亲和力有密切关系.TGF-β的信号通路在纤维化的发生发展中起重要作用.
전화생장인자β(transforming growth factor-β,TGF-β)시계동화종지염증화조직수복적조절인자,시삼여조공폐섬유화발생적세포인자.TGF-β아단위공능여기충류이급여수체적친화력유밀절관계.TGF-β적신호통로재섬유화적발생발전중기중요작용.
Transforming growth factor-β(TGF-β) is the adjusted factor, involving in progress of pulmonary inflammation, and also involving in chronic tissue reparation. TGF-β is a member of cytokine family involving in pulmonary fibrosis effected by TGF-β. The isoform's activities of TGF-β are closely related to its types and receptors' affinity. The signal pathways of TGF-β are believed to be primarily responsible for pulmonary fibrosis progression.