CAJ | 학술논문

目的探讨扫描电镜技术预测良性与侵蚀性葡萄胎的应用价值.方法运用扫描电镜技术观察葡萄胎90例（良性60例，侵蚀性30例），以10例正常早期胎盘绒毛作对照.在研究方法上，我们把患者血、尿HCG（绒毛膜促性腺激素）测定作为本研究的监测指标，当葡萄胎后12wk血、尿HCG不下降至正常时视为恶性.结果 ①60例良性葡萄胎的血、尿HCG于葡萄胎后12wk内降至正常；30例侵蚀性葡萄胎中，29例HCG于葡萄胎后12wk内超过正常，另有1例于20＋4wk超过正常.②良性与侵蚀性葡萄胎的扫描电镜图像有显著差别：良性葡萄胎绒毛表面的微绒毛丰富，分布均匀.侵蚀性葡萄胎绒毛表面的微绒毛相互融合，形成不规则斑块.结论扫描电镜技术可以用于预测良性与侵蚀性葡萄胎.
목적 탐토소묘전경기술예측량성여침식성포도태적응용개치.방법 운용소묘전경기술관찰포도태90례（량성60례，침식성30례），이10례정상조기태반융모작대조.재연구방법상，아문파환자혈、뇨HCG（융모막촉성선격소）측정작위본연구적감측지표，당포도태후12wk혈、뇨HCG불하강지정상시시위악성.결과 ①60례량성포도태적혈、뇨HCG우포도태후12wk내강지정상；30례침식성포도태중，29례HCG우포도태후12wk내초과정상，령유1례우20＋4wk초과정상.②량성여침식성포도태적소묘전경도상유현저차별：량성포도태융모표면적미융모봉부，분포균균.침식성포도태융모표면적미융모상호융합，형성불규칙반괴.결론 소묘전경기술가이용우예측량성여침식성포도태.
AIM To investigate the practical value of scanning electronmicroscopical technique (SEMT) in the early diagnosis of benign and invasive hydatidiform moles. METHODS SEMT was performed to observe 90 cases with hydatidiform moles (60 cases with benign and 30 cases with invasive hydatidiform moles) and 10 cases with normal placental villis as the control. Set as the differential criterion for our study was the assay HCG (human chorionic gonadotropin) of both the blood and the urine of the patients. Those whose HCG of both the blood and the urine after hydatidiform moles did not drop to the normal level in 12 weeks were regarded as with the malignant moles. RESULTS ① HCG of both the blood and the urine of 60 benign hydatidiform moles decreased to the normal level (<3.1 IU·L-1) in 12 weeks after hydatidiform moles; HCG of 29 invasive hydatidiform moles was higher than the normal level (>3.1 IU·L-1) in 12 weeks and that of 1 hydatidiform mole increased after 144 days (>3.1 IU·L-1). ② There was a significant difference in image between the benign and the invasive hydatidiform moles. On the surface of the benign hydatidiform moles, there were rich and evenly distributed microvilli, but on the surface of the invasive hydatidiform moles, the microvilli were mixed into irregular spots. CONCLUSION The above results indicate that SEMT can be used to predict the benign and invasive hydatidiform moles.