中国实用眼科杂志
中國實用眼科雜誌
중국실용안과잡지
CHINESE JOURNAL OF PRACTICAL OPHTHALMOLOGY
2011年
3期
217-220
,共4页
正常眼压性青光眼%OCT%中央角膜厚度
正常眼壓性青光眼%OCT%中央角膜厚度
정상안압성청광안%OCT%중앙각막후도
Normal tension glaucoma%Optical coherence tomography%Central corneal thickness
目的 探讨薄角膜正常眼压性青光眼(NTG)患者视盘周围视网膜神经纤维层(RNFL)厚度及视盘结构的OCT特征.方法 采用OCT对21例(42只眼)中央角膜厚度(CCT)低于正常人群范围(＜500μm)的正常眼压性青光眼患者进行RNFL及视盘扫描,并根据其CCT值分为:组1(480μm≤CCT＜500μm)和组2(460μm≤CCT＜480μm),比较分析两组RNFL厚度、视盘参数及30.中心视野指数.结果 两组患者的OCT检测参数包括Avg.Thick、Savg、Iavg、Navg、Tavg差异无统计学意义(P＞0.05),Max-Min值差异有统计学意义(P＜0.05);视盘参数(垂直盘沿容积值等)、视野参数(MD、MS值)差异无统计学意义(P＞0.05).两组患者的RNFL平均厚度与视野平均缺损值MD呈强且负的直线关系(r=-0.602,P=0.000).结论 OCT能对NTG患者视盘及视网膜神经纤维层做出定量测量和分析,且与视野检测指标有良好的相关性,在NTG的早期诊断中有重要意义;薄角膜NTG患者的角膜厚度水平与视网膜神经纤维层缺损程度无明显相关.
目的 探討薄角膜正常眼壓性青光眼(NTG)患者視盤週圍視網膜神經纖維層(RNFL)厚度及視盤結構的OCT特徵.方法 採用OCT對21例(42隻眼)中央角膜厚度(CCT)低于正常人群範圍(＜500μm)的正常眼壓性青光眼患者進行RNFL及視盤掃描,併根據其CCT值分為:組1(480μm≤CCT＜500μm)和組2(460μm≤CCT＜480μm),比較分析兩組RNFL厚度、視盤參數及30.中心視野指數.結果 兩組患者的OCT檢測參數包括Avg.Thick、Savg、Iavg、Navg、Tavg差異無統計學意義(P＞0.05),Max-Min值差異有統計學意義(P＜0.05);視盤參數(垂直盤沿容積值等)、視野參數(MD、MS值)差異無統計學意義(P＞0.05).兩組患者的RNFL平均厚度與視野平均缺損值MD呈彊且負的直線關繫(r=-0.602,P=0.000).結論 OCT能對NTG患者視盤及視網膜神經纖維層做齣定量測量和分析,且與視野檢測指標有良好的相關性,在NTG的早期診斷中有重要意義;薄角膜NTG患者的角膜厚度水平與視網膜神經纖維層缺損程度無明顯相關.
목적 탐토박각막정상안압성청광안(NTG)환자시반주위시망막신경섬유층(RNFL)후도급시반결구적OCT특정.방법 채용OCT대21례(42지안)중앙각막후도(CCT)저우정상인군범위(＜500μm)적정상안압성청광안환자진행RNFL급시반소묘,병근거기CCT치분위:조1(480μm≤CCT＜500μm)화조2(460μm≤CCT＜480μm),비교분석량조RNFL후도、시반삼수급30.중심시야지수.결과 량조환자적OCT검측삼수포괄Avg.Thick、Savg、Iavg、Navg、Tavg차이무통계학의의(P＞0.05),Max-Min치차이유통계학의의(P＜0.05);시반삼수(수직반연용적치등)、시야삼수(MD、MS치)차이무통계학의의(P＞0.05).량조환자적RNFL평균후도여시야평균결손치MD정강차부적직선관계(r=-0.602,P=0.000).결론 OCT능대NTG환자시반급시망막신경섬유층주출정량측량화분석,차여시야검측지표유량호적상관성,재NTG적조기진단중유중요의의;박각막NTG환자적각막후도수평여시망막신경섬유층결손정도무명현상관.
Objective To investigate the thickness changes of peripapillary retinal nerve fiber layer (RNFL) in normal tension glaucoma (NTG) with thin cornea measured by optical coherence tomography (OCT).Methods Twenty-one NTG patients (42 eyes) with thin cornea were divided into two groups according to their central corneal thickness (CCT):group 1 (480μm≤CCT＜500μm) and group 2 (460μm≤CCT＜480μm),and analysis the different results of OCT scan and visual outcome in two groups.Results There were no significant differences in OCT parameters of Avg.,Thick,Savg,Iavg,Navg and Tavg among the two groups (P ＞0.05),while Max-Min was lower in group 2 (P ＜0.05);There were also no significant differences in the optic nerve head analysis results,visual field mean defect (MD) and mean sensitivity (MS) among two groups (P＞0.05).The average RNFL thickness and MD showed a strong and negative linear relationship(r =-0.602,P =0.000).Conclusions OCT can make quantitative measurement and analysis of optic disc and RNFL for NTG patients,and has a good correlation with vision field.It has important significance in the early diagnosis of NTG.For NTG patients with thin corneas,there is no significant correlation between the level of CCT and extent of retinal nerve fiber layer defect.
