中华放射学杂志
中華放射學雜誌
중화방사학잡지
Chinese Journal of Radiology
2011年
12期
1216-1219
,共4页
李小虎%余永强%王万勤%刘斌%张翼飞%张帅%陈垦%汪世玉%万宇辉%吴兴旺%周勇%王乐%杨琪放%汪洁
李小虎%餘永彊%王萬勤%劉斌%張翼飛%張帥%陳墾%汪世玉%萬宇輝%吳興旺%週勇%王樂%楊琪放%汪潔
리소호%여영강%왕만근%류빈%장익비%장수%진은%왕세옥%만우휘%오흥왕%주용%왕악%양기방%왕길
肾结石%体层摄影术%X线计算机%对比研究
腎結石%體層攝影術%X線計算機%對比研究
신결석%체층섭영술%X선계산궤%대비연구
kidney calculi%Tomography%X-ray computed%Compative study
目的 探讨能谱CT在体外区分肾结石成分的价值.方法 168枚经外科手术取出的肾结石,分别置于猪肾中.行能谱扫描( GSI)及常规120 kVp扫描.测量计算GSI图像上结石的有效原子序数(Zeff)、钙水比值(CWR)、能谱衰减曲线斜率、50 keV单能量CT值及120 kVp混合能量CT值,并采用方差分析或秩和检验比较各组结石上述指标的差异.分别采用红外光谱分析仪测定其成分,成分单一的结石108枚,其中尿酸类结石组13枚、鸟粪石结石组24枚、胱氨酸结石组14枚、磷酸钙结石组18枚、草酸钙结石组39枚.结果 5组结石的Zeff、CWR、50 keV单能量CT值、120 kVp混合能量CT值及能谱衰减曲线斜率分别为:尿酸类结石组为7.4±0.4、0.0085±0.0021、(503±168) HU、(495±106) HU、-0.77、鸟粪石结石组为11.8±0.9、0.1743±0.0677、(1056±290) HU、(799±165) HU、18.72,胱氨酸结石组为11.2±0.6、0.1253±0.0297、(740±172)HU、(565±129) HU、12.79,磷酸钙结石组为16.0±0.4、0.6781±0.0952、(2567±178) HU、(1602±200) HU、37.14,草酸钙结石组为15.4 ±0.4、0.5683±0.0759、( 2267±385) HU、( 1489±284) HU、36.36,组间差异均有统计学意义(P值均＜0.01).组内两两比较,有效原子序数、钙水比值及50 keV单能量CT值差异均有统计学意义(P值均＜0.05).结论 能谱CT成像为区分肾结石成分提供了新的方法,有效原子序数、钙水比值及50 keV单能量CT值,3个指标均可以明显区分尿酸类、鸟粪石类、胱氨酸、磷酸钙类及草酸钙类结石.
目的 探討能譜CT在體外區分腎結石成分的價值.方法 168枚經外科手術取齣的腎結石,分彆置于豬腎中.行能譜掃描( GSI)及常規120 kVp掃描.測量計算GSI圖像上結石的有效原子序數(Zeff)、鈣水比值(CWR)、能譜衰減麯線斜率、50 keV單能量CT值及120 kVp混閤能量CT值,併採用方差分析或秩和檢驗比較各組結石上述指標的差異.分彆採用紅外光譜分析儀測定其成分,成分單一的結石108枚,其中尿痠類結石組13枚、鳥糞石結石組24枚、胱氨痠結石組14枚、燐痠鈣結石組18枚、草痠鈣結石組39枚.結果 5組結石的Zeff、CWR、50 keV單能量CT值、120 kVp混閤能量CT值及能譜衰減麯線斜率分彆為:尿痠類結石組為7.4±0.4、0.0085±0.0021、(503±168) HU、(495±106) HU、-0.77、鳥糞石結石組為11.8±0.9、0.1743±0.0677、(1056±290) HU、(799±165) HU、18.72,胱氨痠結石組為11.2±0.6、0.1253±0.0297、(740±172)HU、(565±129) HU、12.79,燐痠鈣結石組為16.0±0.4、0.6781±0.0952、(2567±178) HU、(1602±200) HU、37.14,草痠鈣結石組為15.4 ±0.4、0.5683±0.0759、( 2267±385) HU、( 1489±284) HU、36.36,組間差異均有統計學意義(P值均＜0.01).組內兩兩比較,有效原子序數、鈣水比值及50 keV單能量CT值差異均有統計學意義(P值均＜0.05).結論 能譜CT成像為區分腎結石成分提供瞭新的方法,有效原子序數、鈣水比值及50 keV單能量CT值,3箇指標均可以明顯區分尿痠類、鳥糞石類、胱氨痠、燐痠鈣類及草痠鈣類結石.
목적 탐토능보CT재체외구분신결석성분적개치.방법 168매경외과수술취출적신결석,분별치우저신중.행능보소묘( GSI)급상규120 kVp소묘.측량계산GSI도상상결석적유효원자서수(Zeff)、개수비치(CWR)、능보쇠감곡선사솔、50 keV단능량CT치급120 kVp혼합능량CT치,병채용방차분석혹질화검험비교각조결석상술지표적차이.분별채용홍외광보분석의측정기성분,성분단일적결석108매,기중뇨산류결석조13매、조분석결석조24매、광안산결석조14매、린산개결석조18매、초산개결석조39매.결과 5조결석적Zeff、CWR、50 keV단능량CT치、120 kVp혼합능량CT치급능보쇠감곡선사솔분별위:뇨산류결석조위7.4±0.4、0.0085±0.0021、(503±168) HU、(495±106) HU、-0.77、조분석결석조위11.8±0.9、0.1743±0.0677、(1056±290) HU、(799±165) HU、18.72,광안산결석조위11.2±0.6、0.1253±0.0297、(740±172)HU、(565±129) HU、12.79,린산개결석조위16.0±0.4、0.6781±0.0952、(2567±178) HU、(1602±200) HU、37.14,초산개결석조위15.4 ±0.4、0.5683±0.0759、( 2267±385) HU、( 1489±284) HU、36.36,조간차이균유통계학의의(P치균＜0.01).조내량량비교,유효원자서수、개수비치급50 keV단능량CT치차이균유통계학의의(P치균＜0.05).결론 능보CT성상위구분신결석성분제공료신적방법,유효원자서수、개수비치급50 keV단능량CT치,3개지표균가이명현구분뇨산류、조분석류、광안산、린산개류급초산개류결석.
Objective To evaluate the feasibility of determining the chemical composition of kidney stones using gemstone spectral imaging ( GSI ).Methods One hundred and sixty eight extracted human kidney stones immersed in a 10 cm deep water tank underwent CT (Discovery CT750 HD) scans with GSI mode and conventional polychromatic imaging ( CPI,120 kVp) mode.All GSI data were transferred to Workstation AW 4.4 to acquire monochromatic images of 50 keY,effective atomic number (Zeff) mapping images,water (calcium)-based images and calcium (Water)-based images with GSI Viewer.CT numbers of stones were measured and compared at 50 keV monochromatic images and 120 kVp polychromatic images,the mean Zeff,calcium density and water density were measured at Zeff mapping images,Calcium (Water) -based images and Water (Calcium)-based images,respectively.The mean Zeff,spectral HU curve slope and calcium water ratio (CWR) were compared with ANOVA and Wilcoxon test.The composition of kidney stones was determined by infrared spectrometer after CT examination.According to the result of stone composition determined by infrared spectroscopy,108 pure kidney stones were divided into five groups:Uric acid stones ( UA,n = 13 ),struvite stones ( STR,n = 24),cystine stones ( CYS,n = 14),calcium phosphate stones ( CaP,n = 18),and calcium oxalate stones ( COX,n = 39).Results The mean Zeff,CWR,the mean CT numbers at 50 keV images,120 kVp images and spectral HU curve slope of each group were listed as the following:UA [ 7.4 ± 0.4,0.0085 ± 0.0021,( 503 ± 168 ) HU,(495 ± 106 ) HU and - 0.77 ] ; STR [ 11.8 ± 0.9,0.1743 ± 0.0677,( 1056 ± 290 ) HU,( 799 ± 165 ) HU and 18.72 ] ; CYS [ 11.2 ± 0.6,0.1253 ± 0.0297,( 740 ± 172 ) HU,( 565 ± 129 ) HU and 12.79 ] ; CaP [ 16.0 ± 0.4,0.6781 ± 0.0952,( 2567 ±178 ) HU,( 1602 ± 200 ) HU and 37.14 ] ; COX [ 15.4 ± 0.4,0.5683 ± 0.0759,( 2267 ± 385 ) HU,( 1489 ±284) HU and 36.36 ],there were significant differences among groups ( P ＜ 0.01 ).The differences in the mean Zeff,CRW,spectral HU curve slope were statistically significant among the five groups ( P ＜ 0.05 ).Conclusion Spectral CT imaging provides a new method to characterize the kidney stones with the information orovided by mean Zeff,CRW and the CT numbers at 50 keV.
