CAJ | 학술논문

目的探讨对比增强超声造影对胃癌术前T分期的临床诊断价值.方法采用六氟化硫微气泡造影剂和连续实时成像的对比脉冲序列技术,对8例健康志愿者进行超声造影,并与正常胃螺旋CT增强造影结果相对照;对62例经胃镜活检证实的胃癌患者术前行超声造影,并与术后病理检查结果对照.结果 8例正常胃壁在对比增强超声造影动脉期、平衡期呈3层结构,门脉期呈单层结构.3层结构中内层轻度增强相应于黏膜层;中间层低增强相应于黏膜下层;外层明显增强相应于肌肉-浆膜层.62例经腹超声检查胃癌术前T分期的准确率为72.9%,对比增强超声造影T分期准确率为88.1%,两者T分期的差异有统计学意义(χ~2=4.37,P=0.036).结论正常胃壁在对比增强超声造影下可显示单层或3层结构,这为判断胃癌浸润深度提供了理论基础.对比增强超声造影对胃癌术前T分期具有较高的临床应用价值.
목적 탐토대비증강초성조영대위암술전T분기적림상진단개치.방법 채용륙불화류미기포조영제화련속실시성상적대비맥충서렬기술,대8례건강지원자진행초성조영,병여정상위라선CT증강조영결과상대조;대62례경위경활검증실적위암환자술전행초성조영,병여술후병리검사결과대조.결과 8례정상위벽재대비증강초성조영동맥기、평형기정3층결구,문맥기정단층결구.3층결구중내층경도증강상응우점막층;중간층저증강상응우점막하층;외층명현증강상응우기육-장막층.62례경복초성검사위암술전T분기적준학솔위72.9%,대비증강초성조영T분기준학솔위88.1%,량자T분기적차이유통계학의의(χ~2=4.37,P=0.036).결론 정상위벽재대비증강초성조영하가현시단층혹3층결구,저위판단위암침윤심도제공료이론기출.대비증강초성조영대위암술전T분기구유교고적림상응용개치.
Objective To investigate the diagnostic value of contrast-enhanced ultrasonograpby (CEUS) in preoperative T-staging of gastric cancer. Methods A sulfur hexafluoride-filled microbubble ultrasound contrast agent and a continuous real-time imaging technique of contrast pulse sequencing were used. Normal gastric wall was examined by CEUS in 8 healthy volunteers and the results were compared with the findings on multislice computed tomography. Sixty-two patients with gastric cancer proved by biopsies who received preoperative CEUS examination were involved in this study, and the CEUS result was compared with postoperative pathological findings. Results The normal gastric wall presented a one-layer structure in the portal venous phase and a three-layer structure in the arterial and equilibrium phase including a slightly hyper-enhanced inner layer, a hypo-enhanced intermediate layer,and a markedly hyper-enhanced outer layer, which corresponded histologically to the mucosal,submucosal, and muscular-serosal layer, respectively. The accuracy of transabdominal ultrasonography and CEUS in determining the T stage of gastric cancer was 72.9% and 88.1% respectively, and the difference was statistically significant (χ~2=4.37, P=0.036). Conclusions CEUS shows the normal gastric wall as a one-or a three-layer stmcture, which provides a theory base for CEUS in preoperative T-staging of gastric cancer. CEUS is a useful diagnostic method for preoperative T-staging of gastric cancer.